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CAS 864291-30-5

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2,4-dichloro-6-(trifluoromethyl)quinazoline

Description:
2,4-Dichloro-6-(trifluoromethyl)quinazoline is a synthetic organic compound belonging to the quinazoline family, characterized by its fused bicyclic structure. This compound features two chlorine atoms at the 2 and 4 positions and a trifluoromethyl group at the 6 position of the quinazoline ring, which significantly influences its chemical properties and reactivity. It is typically a solid at room temperature and exhibits moderate solubility in organic solvents. The presence of halogen substituents enhances its potential for biological activity, making it of interest in pharmaceutical research, particularly in the development of anticancer agents and other therapeutic applications. The trifluoromethyl group is known to increase lipophilicity, which can affect the compound's pharmacokinetics. Additionally, 2,4-dichloro-6-(trifluoromethyl)quinazoline may exhibit specific interactions with biological targets, contributing to its utility in medicinal chemistry. As with many halogenated compounds, it is essential to handle it with care due to potential toxicity and environmental impact.
Formula:C9H3Cl2F3N2
InChI:InChI=1/C9H3Cl2F3N2/c10-7-5-3-4(9(12,13)14)1-2-6(5)15-8(11)16-7/h1-3H
SMILES:c1cc2c(cc1C(F)(F)F)c(Cl)nc(Cl)n2
Synonyms:
  • Quinazoline, 2,4-dichloro-6-(trifluoromethyl)-
  • 2,4-Dichloro-6-(trifluoromethyl)quinazoline
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