CAS 864357-87-9

Simvastatin EP Impurity M (Simvastatin Ethyl Ester)

CAS: 864357-87-9

Formula: C₂₇H₄₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 464.64

Ref: 4Z-S-1213

Ethyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-Dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate

CAS: 864357-87-9

Color and Shape: Neat

Ref: 86-MM0158.21

Simvastatin EP Impurity M

CAS: 864357-87-9

Formula: C₂₇H₄₄O₆

Molecular weight: 464.64

Ref: ST-EA-CP-S4013

Simvastatin Hydroxy Acid Ethyl Ester

CAS: 864357-87-9

Applications An impurity in Simvastatin (S485000).
References Sankar, D. et al.: Asian J. Chem., 21, 4294 (2009); Vuletic, M. et al.: J. Pharmac. Biomed. Anal., 37, 715 (2005);

Formula: C₂₇H₄₄O₆

Color and Shape: Off-White

Molecular weight: 464.63

Ref: TR-S485035

Simvastatin hydroxy acid ethyl ester

CAS: 864357-87-9

Simvastatin hydroxy acid ethyl ester is a solvated form of simvastatin, an investigational drug for the treatment of dyslipidemia. The ammonium salt was prepared by alcoholysis with ethanol. The elution process was carried out using an acetonitrile-water mixture and chromatography on silica gel. Preparation methods were investigated to determine the best preparative procedure that would yield pure material. This compound has been investigated as a possible therapeutic agent for the treatment of midbody diseases such as familial amyloidotic polyneuropathy and Alzheimer's disease.

Formula: C₂₇H₄₄O₆

Purity: Min. 95%

Color and Shape: Colourless To Pale Yellow Liquid

Molecular weight: 464.63 g/mol

Ref: 3D-IS27836