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CAS 864445-60-3

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Jwh 249

Description:
JWH-249 is a synthetic cannabinoid that belongs to a class of compounds known as indole derivatives. It is structurally related to other cannabinoids and is known for its psychoactive effects, which mimic those of natural cannabinoids found in cannabis. JWH-249 acts primarily as a potent agonist at the cannabinoid receptors, particularly CB1 and CB2, influencing various physiological processes such as mood, appetite, and pain sensation. The compound is often studied for its potential therapeutic applications, although it is also associated with recreational use and legal concerns in many jurisdictions. Due to its synthetic nature, JWH-249 may exhibit different pharmacokinetic properties compared to natural cannabinoids, including variations in metabolism and duration of action. As with many synthetic cannabinoids, there are concerns regarding safety, potential for abuse, and the unpredictability of effects, which can vary significantly among users. Research on JWH-249 is ongoing to better understand its pharmacological profile and implications for health.
Formula:C21H22BrNO
InChI:InChI=1S/C21H22BrNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3
InChI key:InChIKey=CGQRVOHECAULLB-UHFFFAOYSA-N
SMILES:C(CC1=C(Br)C=CC=C1)(=O)C=2C=3C(N(CCCCC)C2)=CC=CC3
Synonyms:
  • Ethanone, 2-(2-bromophenyl)-1-(1-pentyl-1H-indol-3-yl)-
  • JWH-249;JWH249
  • 2-(2-bromophenyl)-1-(1-pentylindol-3-yl)ethanone
  • 2-(2-BroMophenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone
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  • JWH-249
    Biosynth
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    JWH-249

    Controlled Product
    CAS:
    JWH-249 is a synthetic cannabinoid that has been shown to bind with the CB2 receptor. It is one of the most potent hydrophobic synthetic cannabinoids, with an EC50 of 1.8 nM for cb2 receptor binding and 0.4 nM for cb1 receptor binding. JWH-249 has been shown to protect against muscle damage in animal models, which may be due to its ability to inhibit the release of proinflammatory cytokines from macrophages. The experimental techniques used in JWH-249 research include chemical ionization (CI) mass spectrometry, spectroscopy, cell culture, and analytical methods such as reaction monitoring and mass spectrometry. These techniques are used to identify the chemical structure and purity of JWH-249, as well as monitor its metabolic profile and toxic effects on cells.
    Purity:Min. 95%

    Ref: 3D-CJ175180

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