CAS 86482-18-0

Clavulanic acid-ticarcillin mixt.

Description:

Clavulanic acid-ticarcillin mixture, identified by the CAS number 86482-18-0, is a combination of two pharmacologically active compounds: clavulanic acid and ticarcillin. Clavulanic acid is a beta-lactamase inhibitor that enhances the efficacy of ticarcillin, a penicillin antibiotic, against beta-lactamase-producing bacteria. This mixture is primarily used in clinical settings to treat infections caused by susceptible organisms, particularly those resistant to other antibiotics due to the production of beta-lactamases. The combination works synergistically, allowing ticarcillin to maintain its antibacterial activity. Clavulanic acid itself is characterized by its ability to irreversibly bind to beta-lactamase enzymes, thereby preventing the breakdown of ticarcillin. The mixture is typically administered parenterally and is effective against a broad spectrum of Gram-positive and Gram-negative bacteria. Its pharmacokinetics involve rapid absorption and distribution, with renal excretion being the primary route of elimination. Overall, the clavulanic acid-ticarcillin mixture is a valuable therapeutic option in the management of various bacterial infections.

Formula: C₁₅H₁₆N₂O₆S₂·C₈H₉NO₅

InChI: InChI=1S/C15H16N2O6S2.C8H9NO5/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);1,6-7,10H,2-3H2,(H,12,13)/b;4-1-/t7-,8-,9+,12-;6-,7-/m11/s1

InChI key: InChIKey=XWMVMWTVLSLJGY-FAJPTIRJSA-N

SMILES: C(O)(=O)[C@@H]\1N2[C@](O/C1=C\CO)(CC2=O)[H].N(C([C@H](C(O)=O)C=1C=CSC1)=O)[C@H]2[C@@]3(N([C@@H](C(O)=O)C(C)(C)S3)C2=O)[H]

Synonyms:

• 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, mixt. with (2S,5R,6R)-6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-, mixt. contg.
• 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, mixt. with (2S,5R,6R)-6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, [2R-(2α,3Z,5α)]-, mixt. with [2S-[2α,5α,6β(S*)]]-6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, mixt. contg.

Timentin

CAS: 86482-18-0

Timentin is a peptide that has been shown to activate receptors, ion channels and ligands. It has also been shown to inhibit the synthesis of protein in cells. Timentin may be used as a research tool for studying the activation of protein-receptor interactions, or as an inhibitor for studying the inhibition of protein synthesis. Timentin is a high purity compound with a CAS number of 86482-18-0.

Formula: C₂₃H₂₅N₃O₁₁S₂

Purity: Min. 95%

Molecular weight: 583.6 g/mol

Ref: 3D-LDA48218