CAS 86562-10-9

Guanosine, cyclic3',5'-[(S)-hydrogen phosphorothioate] (9CI)

Description:

Guanosine, cyclic 3',5'-[(S)-hydrogen phosphorothioate] (9CI), with the CAS number 86562-10-9, is a nucleotide analog characterized by its cyclic structure and the presence of a phosphorothioate group. This compound features a guanosine base linked to a cyclic phosphate moiety, which is modified by the substitution of an oxygen atom with a sulfur atom in the phosphate group, enhancing its stability against enzymatic degradation. The (S)-configuration of the phosphorothioate indicates the specific stereochemistry of the sulfur atom, which can influence the biological activity and interaction with nucleic acid targets. Guanosine derivatives are known to play significant roles in cellular signaling and metabolism, and the cyclic form can participate in various biochemical processes, including those related to RNA function. The unique properties of this compound make it of interest in medicinal chemistry and molecular biology, particularly in the development of therapeutic agents and tools for studying nucleic acid interactions.

Formula: C₁₀H₁₂N₅O₆PS

Synonyms:

• Guanosine,cyclic 3',5'-(hydrogen phosphorothioate), (S)-
• 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, guanosine deriv.

Sp-Guanosine 3′,5′-cyclic monophosphorothioate triethylammonium salt

CAS: 86562-10-9

Formula: C₁₀H₁₂N₅O₆PS·C₆H₁₅N

Molecular weight: 462.5

Ref: 7W-GM8282