CAS 866021-03-6

1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-,trihydrochloride

Description:

1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-, trihydrochloride is a complex organic compound characterized by its unique bicyclic structure, which includes a pyrrole and a pyridine moiety. This compound is typically a white to off-white solid and is soluble in water due to the presence of multiple hydrochloride groups, which enhance its ionic character. The presence of the piperazine ring contributes to its pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of psychoactive drugs. The chlorophenyl substituent may influence its biological activity and receptor binding affinity. As a trihydrochloride salt, it is often used in research settings for its stability and ease of handling. The compound's molecular interactions and potential therapeutic applications are subjects of ongoing investigation, particularly in the context of neurological and psychiatric disorders. Safety data and handling precautions should be observed, as with all chemical substances, to ensure proper laboratory practices.

Formula: C₁₈H₁₉ClN₄ClH

L-745,870Trihydrochloride

CAS: 866021-03-6

Formula: C₁₈H₂₂Cl₄N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 436.2061

Ref: IN-DA01E5K3

L-745870 trihydrochloride

CAS: 866021-03-6

L-745870 trihydrochloride

Purity: ≥95%

Molecular weight: 436.21g/mol

Ref: 54-BUP08385

L-745870 trihydrochloride

CAS: 866021-03-6

L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.

Formula: C₁₈H₂₂Cl₄N₄

Purity: 97.52%

Color and Shape: Solid

Molecular weight: 436.21

Ref: TM-T22904

L-745,870 Trihydrochloride

Controlled Product

CAS: 866021-03-6

Applications L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.
References Bristow, L., et al.: Trends in Pharma. Sci., 18, 186 (1997); Zhang, K., et al.: Neropsychopharma., 29, 1648 (2004)

Formula: C₁₈H₁₉ClN₄·3ClH

Color and Shape: Neat

Molecular weight: 436.206

Ref: TR-L009800

L-745,870 Trihydrochloride

CAS: 866021-03-6

L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.

Formula: C₁₈H₂₂Cl₄N₄

Purity: Min. 95%

Molecular weight: 436.2 g/mol

Ref: 3D-RJB02103