CAS: 86639-52-3 - 7-Ethyl-10-hydroxycamptothecin

Formula: C₂₂H₂₀N₂O₅

InChI: InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1

InChI key: InChIKey=FJHBVJOVLFPMQE-QFIPXVFZSA-N

SMILES: O=C1OCC=2C(=O)N3C(=CC2C1(O)CC)C=4N=C5C=CC(O)=CC5=C(C4C3)CC

Synonyms:

• (19S)-10,19-Diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (S)-Sn 38
• 10-Hydroxy-7-ethylcamptothecin
• 1H-Pyrano3,4:6,7Indolizino1,2-Bquinoline-3,14(4H,12H)-Dione, 4-Ethyl-4,10-Dihydroxy-
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (S)-
• 4,11-Diethyl-4,9-Dihydroxy-1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione
• 4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 7-Ethyl-10-Hydroxy Camptothecin
• 7-Ethyl-10-Hydroxy-Camptothecine
• 7-Ethyl-10-hydroxy-20(S)-camptothecin
• 7-Ethyl-10-hydroxycamptothecine
• Intermediate of Irinotecan 1
• SN 38 (pharmaceutical)
• SN 38 lactone
• Sn-38

7-Ethyl-10-hydroxycamptothecin

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Purity: >98.0%(HPLC)
• Color and Shape: White to Yellow to Green powder to crystal
• Molecular weight: 392.41

Irinotecan Related Compound B ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)

CAS: 86639-52-3

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

• Formula: C₂₂H₂₀N₂O₅
• Color and Shape: Yellow Off-White Powder
• Molecular weight: 392.13722

7-Ethyl-10-hydroxycamptothecin

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Purity: ≥ 98.0%
• Color and Shape: Off-white to yellow powder
• Molecular weight: 392.40

Irinotecan EP Impurity E (Irinotecan USP Related Compound B, (S)-7-Ethyl-10-Hydroxy Camptothecin)

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Color and Shape: Pale Yellow Solid
• Molecular weight: 392.41

7-Ethyl-10-hydroxycamptothecin ((S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 392.40

7-Ethyl-10-Hydroxycamptothecin

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Purity: 95%~99%
• Molecular weight: 392.411

SN-38

CAS: 86639-52-3

SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, …

• Formula: C₂₂H₂₀N₂O₅
• Purity: 99.97%
• Color and Shape: Light-Yellow Solid
• Molecular weight: 392.4

7-Ethyl-10-hydroxy-camptothecin

CAS: 86639-52-3

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 392.411

SN-38

CAS: 86639-52-3

• Formula: C₂₂H₂₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 392.40

7-Ethyl-10-hydroxycamptothecin

CAS: 86639-52-3

7-Ethyl-10-hydroxycamptothecin (also known as SN38) is a metabolite of irinotecan hydrochloride (CPT-11). SN38 is a …

• Formula: C₂₂H₂₀N₂O₅
• Purity: Min. 98 Area-%
• Color and Shape: Off-White Yellow Powder
• Molecular weight: 392.4 g/mol

SN-38-d5

CAS: 86639-52-3

• Formula: C₂₂H₁₅D₅N₂O₅
• Molecular weight: 397.435

SN-38-13C3

CAS: 86639-52-3

• Formula: C₁₉C₃H₂₀N₂O₅
• Molecular weight: 395.383