Topoisomerase
Topoisomerases are enzymes that regulate the topology of DNA during processes such as replication, transcription, and chromosome segregation by introducing transient breaks into the DNA strands to relieve torsional stress. Topoisomerase inhibitors interfere with this process, leading to the accumulation of DNA breaks and the induction of cell death, particularly in rapidly dividing cells. These inhibitors are widely used as chemotherapeutic agents in cancer treatment. At CymitQuimica, we offer a broad range of high-quality topoisomerase inhibitors to support your research in DNA replication, cancer therapy, and cell cycle regulation.
Found 126 products for "Topoisomerase".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Ciprofloxacin
CAS:Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!Formula:C17H18FN3O3Purity:98.77% - 99.91%Color and Shape:White PowderMolecular weight:331.34Flumequine
CAS:Flumequine (R-802) is a broad-spectrum antibiotic targeting DNA gyrase and topoisomerase IV in Gram-positive and Gram-negative bacteria.Formula:C14H12FNO3Purity:99.31% - 99.4%Color and Shape:White SolidMolecular weight:261.25Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFormula:C27H29NO10·HClPurity:96.21% - 99.53%Color and Shape:Red SolidMolecular weight:563.99Ref: TM-T1511
5mg34.00€10mg52.00€1mL*10mM (DMSO)59.00€25mg87.00€50mg113.00€100mg177.00€200mg281.00€500mg442.00€Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurity:98% - 99.99%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Lurtotecan
CAS:Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.Formula:C28H30N4O6Purity:99.18%Color and Shape:Yellow SolidMolecular weight:518.56Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:White SolidMolecular weight:370.38Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow SolidMolecular weight:623.14Ref: TM-T0486L
10mg34.00€25mg49.00€50mg65.00€1mL*10mM (DMSO)71.00€100mg89.00€200mg129.00€500mg254.00€Nalidixic acid sodium salt
CAS:Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.Formula:C12H11N2NaO3Purity:99.72% - 99.95%Color and Shape:White To Off-White PowderMolecular weight:254.22Enoxacin hydrate
CAS:Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.Formula:C15H17FN4O3H2OPurity:99.50%Color and Shape:White SolidMolecular weight:347.34Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Formula:C33H45ClN4O9Purity:98.22% - 99.96%Color and Shape:Yellow SolidMolecular weight:677.18Nalidixic acid
CAS:Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.Formula:C12H12N2O3Purity:99.9% - 99.95%Color and Shape:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Molecular weight:232.24Topotecan hydrochloride
CAS:Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formula:C23H24ClN3O5Purity:97.88% - 99.41%Color and Shape:SolidMolecular weight:457.92Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Formula:C20H18ClNO4Purity:99.47% - 99.93%Color and Shape:Yellow Crystalline PowderMolecular weight:371.80Teniposide
CAS:Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming a complex with topoisomerase II andFormula:C32H32O13SPurity:97.7% - 99.45%Color and Shape:SolidMolecular weight:656.65Ciprofloxacin monohydrochloride
CAS:Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.Formula:C17H18FN3O3·HClPurity:99.5% - 99.73%Color and Shape:SolidMolecular weight:367.80Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:97.05% - >99.99%Color and Shape:SolidMolecular weight:517.4Epirubicin hydrochloride
CAS:Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.Formula:C27H30ClNO11Purity:98.13% - 99.79%Color and Shape:SolidMolecular weight:579.98Ref: TM-T0125
2mg37.00€5mg52.00€1mL*10mM (DMSO)70.00€10mg84.00€25mg142.00€50mg226.00€100mg308.00€500mg745.00€Gatifloxacin
CAS:Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.Formula:C19H22FN3O4Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:375.39Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48Enoxacin
CAS:Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.Formula:C15H17FN4O3Purity:99.60% - 99.89%Color and Shape:White SolidMolecular weight:320.32
