Topoisomerase
Topoisomerases are enzymes that regulate the topology of DNA during processes such as replication, transcription, and chromosome segregation by introducing transient breaks into the DNA strands to relieve torsional stress. Topoisomerase inhibitors interfere with this process, leading to the accumulation of DNA breaks and the induction of cell death, particularly in rapidly dividing cells. These inhibitors are widely used as chemotherapeutic agents in cancer treatment. At CymitQuimica, we offer a broad range of high-quality topoisomerase inhibitors to support your research in DNA replication, cancer therapy, and cell cycle regulation.
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Nalidixic acid
CAS:389-08-2
Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal …
Formula:
C12H12N2O3
Purity:
99.22% - 99.95%
Color and Shape:
Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)
Molecular weight:
232.24
Ref: TM-T0909
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Cinoxacin
CAS:28657-80-9
Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.
Formula:
C12H10N2O5
Purity:
99.62% - 99.98%
Color and Shape:
Solid
Molecular weight:
262.22
Ref: TM-T0274
| 50mg | 42.00 € | ||
| 100mg | 61.00 € | ||
| 200mg | 89.00 € | ||
| 500mg | 130.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Hycanthone
CAS:3105-97-3
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.
Formula:
C20H24N2O2S
Purity:
98.78%
Color and Shape:
Yellow-Orange Powder (Ntp 1992)
Molecular weight:
356.48
Ref: TM-T15507
| 5mg | 38.00 € | ||
| 10mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Irinotecan hydrochloride trihydrate
CAS:136572-09-3
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.
Formula:
C33H45ClN4O9
Purity:
98.37% - 99.79%
Color and Shape:
Pale Yellow To Yellow Crystalline Powder
Molecular weight:
677.18
Ref: TM-T0486
| 25mg | 42.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 78.00 € | ||
| 200mg | 93.00 € | ||
| 500mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Irinotecan Hydrochloride
CAS:100286-90-6
Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger …
Formula:
C33H39ClN4O6
Purity:
98% - 99.94%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
623.14
Ref: TM-T0486L
| 10mg | 35.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 68.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 134.00 € | ||
| 500mg | 264.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Flumequine
CAS:42835-25-6
Flumequine (R-802) is a broad-spectrum antibiotic targeting DNA gyrase and topoisomerase IV in Gram-positive and …
Formula:
C14H12FNO3
Purity:
98.92% - 99.4%
Color and Shape:
White Crystalline Powder Solid
Molecular weight:
261.25
Ref: TM-T1060
| 1g | 141.00 € | ||
| 50mg | 44.00 € | ||
| 100mg | 55.00 € | ||
| 500mg | 95.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Pazufloxacin Mesylate
CAS:163680-77-1
Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.
Formula:
C16H15FN2O4·CH4O3S
Purity:
99.76% - 99.88%
Color and Shape:
Crystalline Solid
Molecular weight:
414.4
Ref: TM-T1620
| 1g | 156.00 € | ||
| 50mg | 40.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 104.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Levofloxacin hydrate
CAS:138199-71-0
Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin …
Formula:
C18H20FN3O4H2O
Purity:
98.56%
Color and Shape:
Pale Yellow Solid
Molecular weight:
370.38
Ref: TM-T1451
| 1g | 89.00 € | ||
| 100mg | 34.00 € | ||
| 500mg | 68.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Teniposide
CAS:29767-20-2
Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming …
Formula:
C32H32O13S
Purity:
97.70% - 99.45%
Color and Shape:
White Or Off-White Crystalline Powder
Molecular weight:
656.65
Ref: TM-T1523
| 25mg | 59.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 141.00 € | ||
| 200mg | 219.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Enoxacin
CAS:74011-58-8
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Formula:
C15H17FN4O3
Purity:
98.68% - 99.89%
Color and Shape:
Off-White To Yellow Crystals
Molecular weight:
320.32
Ref: TM-T0717L
| 1g | 179.00 € | ||
| 25mg | 40.00 € | ||
| 50mg | 49.00 € | ||
| 100mg | 68.00 € | ||
| 500mg | 124.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Pefloxacin Mesylate
CAS:70458-95-6
Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative …
Formula:
C18H24FN3O6S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
429.46
Ref: TM-T0425
| 1g | 89.00 € | ||
| 5g | 187.00 € | ||
| 200mg | 39.00 € | ||
| 500mg | 61.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Mitoxantrone dihydrochloride
CAS:70476-82-3
Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II …
Formula:
C22H30Cl2N4O6
Purity:
100% - 99.85%
Color and Shape:
Blue-Black Solid From Water Ethanol Solid
Molecular weight:
517.4
Ref: TM-T0158
| 50mg | 54.00 € | ||
| 100mg | 78.00 € | ||
| 500mg | 170.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Berberine chloride
CAS:633-65-8
Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used …
Formula:
C20H18ClNO4
Purity:
98% - 99.8%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
371.8
Ref: TM-T0461
| 5g | 34.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Topotecan hydrochloride
CAS:119413-54-6
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
Formula:
C23H24ClN3O5
Purity:
97.88% - 98.71%
Color and Shape:
White Crystalline Solid
Molecular weight:
457.92
Ref: TM-T1174
| 1g | 500.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 105.00 € | ||
| 100mg | 142.00 € | ||
| 500mg | 338.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Ciprofloxacin monohydrochloride
CAS:93107-08-5
Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.
Formula:
C17H18FN3O3·HCl
Purity:
100% - 99.5%
Color and Shape:
White Or Light Yellow Crystalline Powder
Molecular weight:
367.8
Ref: TM-T0250
| 1g | 64.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Etoposide
CAS:33419-42-0
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex …
Formula:
C29H32O13
Purity:
99.19% - 99.95%
Color and Shape:
Crystals From Methanol Solid
Molecular weight:
588.56
Ref: TM-T0132
| 50mg | 39.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 104.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Ciprofloxacin
CAS:85721-33-1
Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase.
Formula:
C17H18FN3O3
Purity:
98.77% - 99.89%
Color and Shape:
White Powder
Molecular weight:
331.34
Ref: TM-T1640
| 1g | 64.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Doxorubicin hydrochloride
CAS:25316-40-9
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of …
Formula:
C27H29NO11·HCl
Purity:
98% - 99.57%
Color and Shape:
Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
Molecular weight:
579.99
Ref: TM-T1020
| 1g | 261.00 € | ||
| 25mg | 41.00 € | ||
| 50mg | 53.00 € | ||
| 100mg | 75.00 € | ||
| 200mg | 96.00 € | ||
| 500mg | 177.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Ofloxacin
CAS:82419-36-1
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.
Formula:
C18H20FN3O4
Purity:
99.83%
Color and Shape:
Off-White Solid
Molecular weight:
361.37
Ref: TM-T0902
| 1g | 59.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Enoxacin hydrate
CAS:84294-96-2
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
Formula:
C15H17FN4O3H2O
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
347.34
Ref: TM-T0717
| 100mg | 59.00 € | ||
| 200mg | 68.00 € | ||
| 500mg | 87.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
