CAS 866405-64-3

Dorsomorphin

Description:

Dorsomorphin, with the CAS number 866405-64-3, is a small molecule inhibitor primarily known for its role in the study of the AMP-activated protein kinase (AMPK) pathway. It is characterized by its ability to selectively inhibit the activity of AMPK, which is a crucial regulator of cellular energy homeostasis. Dorsomorphin has been shown to influence various biological processes, including metabolism, cell growth, and differentiation. The compound is often utilized in research to explore its effects on metabolic diseases, cancer, and other conditions linked to energy regulation. Structurally, dorsomorphin features a unique arrangement of functional groups that contribute to its biological activity. It is typically administered in laboratory settings for experimental purposes, and its effects are studied in various cell types and animal models. As with many research chemicals, the safety profile and potential therapeutic applications of dorsomorphin continue to be investigated, highlighting its significance in the field of biochemistry and pharmacology.

Formula: C₂₄H₂₅N₅O

InChI: InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2

InChI key: InChIKey=XHBVYDAKJHETMP-UHFFFAOYSA-N

SMILES: O(CCN1CCCCC1)C2=CC=C(C3=CN4C(=C(C=N4)C=5C=CN=CC5)N=C3)C=C2

Synonyms:

• 6-[4-(2-Piperidin-1-Ylethoxy)Phenyl]-3-Pyridin-4-Ylpyrazolo[1,5-A]Pyrimidine
• 6-[4-(2-Piperidine-1-ylethoxy)phenyl]-3-pyridine-4-ylpyrazolo[1,5-a]pyrimidine
• 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine
• Bml-275
• Compound C
• Dorsomorphin
• Pyrazolo[1,5-a]pyrimidine, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-

Dorsomorphin

CAS: 866405-64-3

Formula: C₂₄H₂₅N₅O

Purity: >97.0%(HPLC)

Color and Shape: White to Light orange to Pale yellow green powder to crystal

Molecular weight: 399.50

Ref: 3B-D5394

Dorsomorphin

CAS: 866405-64-3

Formula: C₂₄H₂₅N₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 399.4882

Ref: IN-DA003MZF

Dorsomorphin

CAS: 866405-64-3

Dorsomorphin

Purity: ≥98%

Molecular weight: 399.49g/mol

Ref: 54-BUP13425

6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine

CAS: 866405-64-3

Formula: C₂₄H₂₅N₅O

Purity: ≥ 98.0%

Color and Shape: Light-yellow to yellow powder or solid

Molecular weight: 399.49

Ref: 7W-GL5083

Dorsomorphin

CAS: 866405-64-3

Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.

Formula: C₂₄H₂₅N₅O

Purity: 98% - 99.06%

Color and Shape: Solid

Molecular weight: 399.49

Ref: TM-T1977

6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine

CAS: 866405-64-3

Formula: C₂₄H₂₅N₅O

Purity: 99%

Molecular weight: 399.498

Ref: 10-F232349

Dorsomorphin

CAS: 866405-64-3

Inhibitor of BMP pathway; inhibitor of ALK2 and ALK3 kinases

Formula: C₂₄H₂₅N₅O

Purity: Min. 95%

Molecular weight: 399.49 g/mol

Ref: 3D-BD162565