CAS 866541-93-7

AT101

Description:

AT101, with the CAS number 866541-93-7, is a small molecule that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is primarily recognized for its role as a selective inhibitor of certain proteins involved in cell survival pathways, which may contribute to its anticancer properties. AT101 has been studied for its ability to induce apoptosis in cancer cells, making it a candidate for cancer treatment. The compound is characterized by its specific interactions with target proteins, which can lead to the modulation of various signaling pathways. Additionally, AT101 has shown promise in preclinical studies, demonstrating efficacy against a range of cancer types. Its solubility, stability, and bioavailability are important factors that influence its pharmacological profile. As research continues, further elucidation of its mechanism of action and potential side effects will be crucial for its development as a therapeutic agent.

Synonyms:

• AT101 acetate
• [2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (2R)-, compd. wi

(R)-(-)-Gossypol acetic acid

CAS: 866541-93-7

(R)-(-)-Gossypol acetic acid

Purity: ≥95%

Molecular weight: 578.61g/mol

Ref: 54-BUP09933

(R)-(-)-Gossypol acetic acid

CAS: 866541-93-7

(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.

Formula: C₃₀H₃₀O₈·C₂H₄O₂

Purity: 98.88% - 99.5%

Color and Shape: Solid

Molecular weight: 578.61

Ref: TM-T6396

AT101

Controlled Product

CAS: 866541-93-7

AT101 is a natural compound that inhibits the production of energy in cells. It binds to nuclear DNA, blocking transcription and replication, leading to apoptosis. AT101 has been shown to have significant cytotoxicity against cancer cells in vitro and in vivo. However, it does not show any effect on healthy cells and can be used as an anticancer agent without side effects. The molecular docking analysis of AT101 with mitochondrial proteins reveals that this drug has a high affinity for the mitochondrial protein Mcl-1. Mcl-1 protein is involved in the regulation of anti-apoptotic pathways, which may explain the lack of toxicity on healthy cells.

Formula: C₃₀H₃₀O₈·C₂H₄O₂

Purity: Min. 95%

Molecular weight: 578.61 g/mol

Ref: 3D-RJB54193