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CAS 86708-67-0

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Retinoic acid, ethyl ester, 9-cis-

Description:
Retinoic acid, ethyl ester, 9-cis- is a synthetic derivative of retinoic acid, which is a metabolite of vitamin A. This compound is characterized by its role in various biological processes, particularly in cell growth, differentiation, and embryonic development. It exhibits a unique configuration, specifically the 9-cis isomer, which influences its biological activity and receptor binding properties. The ethyl ester form enhances its lipophilicity, potentially improving its absorption and bioavailability in biological systems. Retinoic acid derivatives are known to interact with nuclear retinoic acid receptors (RARs), leading to modulation of gene expression. This compound is often studied for its therapeutic potential in dermatology, particularly in the treatment of skin disorders such as acne and psoriasis, as well as in cancer research due to its ability to regulate cell proliferation and differentiation. Additionally, it may have implications in developmental biology and regenerative medicine. As with many retinoids, careful consideration of dosage and formulation is essential due to potential side effects and toxicity.
Formula:C22H32O2
InChI:InChI=1S/C22H32O2/c1-7-24-21(23)16-18(3)11-8-10-17(2)13-14-20-19(4)12-9-15-22(20,5)6/h8,10-11,13-14,16H,7,9,12,15H2,1-6H3/b11-8+,14-13+,17-10-,18-16+
InChI key:InChIKey=ZELWYCSDHIFMOP-MTJYDOFUSA-N
SMILES:C(=C/C(=C\C=C\C(=C\C(OCC)=O)\C)/C)\C=1C(C)(C)CCCC1C
Synonyms:
  • Retinoic acid, ethyl ester, 9-cis-
  • Ethyl 9Z-retinoate
  • Ethyl 9-cis-retinoate
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