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CAS 86780-90-7

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Aranidipine

Description:
Aranidipine is a chemical compound classified as a calcium channel blocker, primarily used in the treatment of hypertension and certain cardiovascular conditions. It belongs to the dihydropyridine class of calcium antagonists, which work by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac tissue. This action leads to vasodilation, reducing blood pressure and alleviating the workload on the heart. Aranidipine is characterized by its lipophilicity, which enhances its ability to penetrate cell membranes and exert its pharmacological effects. The compound typically exhibits a long half-life, allowing for once-daily dosing in clinical settings. Additionally, it may have a favorable side effect profile compared to other antihypertensive agents, making it a suitable option for long-term management of hypertension. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications.
Formula:C19H20N2O7
InChI:InChI=1S/C19H20N2O7/c1-10(22)9-28-19(24)16-12(3)20-11(2)15(18(23)27-4)17(16)13-7-5-6-8-14(13)21(25)26/h5-8,17,20H,9H2,1-4H3
InChI key:InChIKey=NCUCGYYHUFIYNU-UHFFFAOYSA-N
SMILES:C(OCC(C)=O)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C(N(=O)=O)C=CC=C2
Synonyms:
  • (+-)-Acetonyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3-methyl 5-(2-oxopropyl) ester
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl 2-oxopropyl ester
  • 3-Methyl 5-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Aranidipine [INN]
  • Ccris 6724
  • Methyl 2-Oxopropyl 2,6-Dimethyl-4-(2-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate
  • Mpc 1304
  • Sapresta
  • Unii-4Y7Ur6X2Po
  • See more synonyms
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