CAS 868-85-9

Phosphonic acid, dimethyl ester

Description:

Phosphonic acid, dimethyl ester, also known as dimethyl phosphonate, is an organophosphorus compound characterized by its phosphonic acid functional group esterified with two methyl groups. It appears as a colorless to pale yellow liquid with a faint odor and is soluble in water and organic solvents. This compound is notable for its use in various applications, including as a flame retardant, in the synthesis of pharmaceuticals, and as a chemical intermediate in the production of agrochemicals. Dimethyl phosphonate exhibits moderate toxicity and can act as a precursor for the synthesis of more complex phosphorus-containing compounds. Its chemical structure includes a phosphorus atom bonded to two methyl groups and a hydroxyl group, which contributes to its reactivity and versatility in chemical reactions. Additionally, it can participate in hydrolysis, leading to the formation of phosphonic acid and methanol. Safety precautions are necessary when handling this substance due to its potential health effects and environmental impact.

Formula: C₂H₇O₃P

InChI: InChI=1/C2H7O3P/c3-1-6(5)2-4/h3-4,6H,1-2H2

InChI key: InChIKey=HZCDANOFLILNSA-UHFFFAOYSA-N

SMILES: P(OC)(OC)=O

Synonyms:

• (Oxido-Lambda~5~-Phosphanediyl)Dimethanol
• Dimethoxy(Oxo)Phosphonium
• Dimethoxyphosphine oxide
• Dimethyl acid phosphite
• Dimethyl hydrogen phosphonate
• Dimethyl phosphite
• Dimethyl phosphonate
• Dimethylphosphit
• Dimethylphosphite
• Dimethylphosphonat
• Fosfonato De Dimetilo
• Hydrogen dimethyl phosphite
• Methyl phosphonate ((MeO)2HPO)
• Methyl phosphonate ((MeO)₂HPO)
• Phosphonate de dimethyle
• Phosphonic acid dimethyl ester
• Phosphonicaciddimethylester
• Phosphorous acid dimethyl ester
• Dimethyl hydrogen phosphite
• dimethylhydrogenphosphonate
• (CH3O)2PHO
• dimethylesterkyselinifosforite(czech)
• Dimethylfosfit
• dimethylphosphorousacid
• Dimethylfosfonat
• dimethylacidphosphite
• dimethoxyphosphineoxide
• Dimethylester kyseliny fosforite
• bis(hydroxymethyl)phosphineoxide
• Dimethyl ester of phosphonic acid

Olaparib Impurity 16 (Dimethyl phosphite)

CAS: 868-85-9

Formula: C₂H₇O₃P

Molecular weight: 110.05

Ref: 4Z-O-032018

Dimethyl Phosphite

Controlled Product

CAS: 868-85-9

Stability Hygroscopic
Applications Dimethyl Phosphite is used as a reagent in the synthesis of 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. It is also used as a reagent in the synthesis of estafiatin phosphonate derivatives which exhibit antibacterial and antifungal activity.
References Suleimen, E.M., et al.: Chem. Nat. Compd., 50, 846 (2014); Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014)

Formula: C₂H₇O₃P

Color and Shape: Neat

Molecular weight: 110.05

Ref: TR-D477605

Dimethyl phosphite

Controlled Product

CAS: 868-85-9

Dimethyl phosphite is a triple-quadrupole mass spectrometry (QMS) technique that is used to identify inorganic acids and their corresponding anions. It can be used for wastewater treatment, as it converts hydrochloric acid into chloride ions. Dimethyl phosphite reacts with hydrophobic substances such as methyl ketones and carbonyl groups, which results in the release of water vapor. The reaction mechanism of dimethyl phosphite is acidolysis, which involves the addition of water molecules to the carbonyl group to form an enol. This process releases energy that is then converted into heat. Dimethyl phosphite has been shown not to be carcinogenic in animal studies.

Formula: C₂H₇O₃P

Purity: Min. 95%

Molecular weight: 110.05 g/mol

Ref: 3D-FD33953

Dimethyl phosphite

CAS: 868-85-9

Formula: C₂H₇O₃P

Molecular weight: 110.05

Ref: ST-EA-CP-O6061