CAS 86811-09-8

Litoxetine

Description:

Litoxetine is a chemical compound classified as a selective serotonin reuptake inhibitor (SSRI), primarily investigated for its potential use in treating depression and anxiety disorders. It is characterized by its ability to enhance serotonin levels in the brain by inhibiting its reabsorption into neurons, thereby increasing its availability in the synaptic cleft. This mechanism is thought to contribute to its antidepressant effects. Litoxetine has a unique chemical structure that distinguishes it from other SSRIs, which may influence its pharmacokinetic and pharmacodynamic properties. The compound has been studied for its efficacy and safety profile, although it may not be widely used in clinical practice compared to more established SSRIs. As with many psychotropic medications, potential side effects can include gastrointestinal disturbances, changes in weight, and effects on sleep patterns. Ongoing research continues to explore its therapeutic potential and the full scope of its pharmacological effects.

Formula: C₁₆H₁₉NO

InChI: InChI=1S/C16H19NO/c1-2-4-15-11-13(5-6-14(15)3-1)12-18-16-7-9-17-10-8-16/h1-6,11,16-17H,7-10,12H2

InChI key: InChIKey=MJJDYOLPMGIWND-UHFFFAOYSA-N

SMILES: C(OC1CCNCC1)C2=CC3=C(C=C2)C=CC=C3

Synonyms:

• 4-(2-Naphthalenylmethoxy)piperidine
• 4-(2-Naphthylmethoxy)piperidine
• 4-(Naphthalen-2-Ylmethoxy)Piperidine
• Litoxetina
• Litoxetina [INN-Spanish]
• Litoxetine [INN]
• Litoxetinum
• Litoxetinum [INN-Latin]
• Piperidine, 4-(2-naphthalenylmethoxy)-
• Sl 81-0385
• Sl 810385
• Unii-9980St005G

Litoxetine

CAS: 86811-09-8

Litoxetine

Purity: ≥98%

Molecular weight: 241.33g/mol

Ref: 54-BUP12423

Litoxetine

Controlled Product

CAS: 86811-09-8

Applications Litoxetine is a Selective serotonin reuptake inhibitor used as an antidepressant. References Rasmussen, B., et al.: British Journal of Clinical Pharmacology, 39, 151 (1995)

Formula: C₁₆H₁₉NO

Color and Shape: Neat

Molecular weight: 241.328

Ref: TR-L469600

Litoxetine-d5 HCl

CAS: 86811-09-8

Formula: C₁₆H₁₄D₅NO·HCl

Molecular weight: 246.36 36.46

Ref: 4Z-L-165002

Litoxetine-D9

Controlled Product

CAS: 86811-09-8

Formula: C₁₆D₉H₁₀NO

Color and Shape: Neat

Molecular weight: 250.384

Ref: TR-L469603

Litoxetine-d9 HCl

CAS: 86811-09-8

Formula: C₁₆H₁₀D₉NO·HCl

Molecular weight: 250.39 36.46

Ref: 4Z-L-165003

Litoxetine

CAS: 86811-09-8

Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.

Formula: C₁₆H₁₉NO

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 241.33

Ref: TM-T67956