CAS 86832-68-0

Carumonam sodium

Description:

Carumonam sodium is a synthetic antibiotic belonging to the class of monobactams, which are characterized by their beta-lactam structure. It is primarily used for its antibacterial properties, particularly against Gram-negative bacteria. The compound exhibits a broad spectrum of activity and is often utilized in clinical settings for treating infections caused by resistant strains. Carumonam sodium is known for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many other antibiotics. This characteristic makes it a valuable option in the treatment of infections where traditional antibiotics may fail. Additionally, it is typically administered via injection, and its pharmacokinetics involve rapid distribution in the body, with renal excretion being a significant pathway for elimination. As with any antibiotic, the potential for resistance development is a concern, necessitating careful use and monitoring in clinical practice. Overall, Carumonam sodium represents an important tool in the ongoing battle against bacterial infections, particularly in an era of increasing antibiotic resistance.

Formula: C₁₂H₁₄N₆O₁₀S₂·2Na

InChI: InChI=1S/C12H14N6O10S2.2Na/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26;;/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26);;/b17-7-;;/t5-,8+;;/m1../s1

InChI key: InChIKey=PGLNDUOTZXKQHS-AHCAJXDVSA-N

SMILES: N(C(/C(=N\OCC(O)=O)/C=1N=C(N)SC1)=O)[C@H]2[C@@H](COC(N)=O)N(S(=O)(=O)O)C2=O.[Na]

Synonyms:

• ({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-({(2S,3S)-2-[(carbamoyloxy)methyl]-4-oxo-1-sulfoazetidin-3-yl}amino)-2-oxoethylidene]amino}oxy)acetic acid
• Acetic acid, [[(2Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, disodium salt
• Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, disodium salt, [2S-[2α,3α(Z)]]-
• Acetic acid,2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-,sodium salt (1:2)
• Ama-1080
• Amasulin
• Carumonam disodium salt
• Carumonam sodium
• Mobactam
• Ro-17-2301/006

Carumonam disodium

CAS: 86832-68-0

Carumonam disodium is a monobactam antibiotic, which is derived from microbial fermentation processes. Its mode of action involves binding to penicillin-binding proteins (PBPs) of susceptible Gram-negative bacteria. This binding inhibits the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall, leading to cell lysis and death.

Formula: C₁₂H₁₄N₆Na₂O₁₀S₂

Purity: Min. 95%

Molecular weight: 512.39 g/mol

Ref: 3D-AC29319

Carumonam Disodium Salt

Controlled Product

CAS: 86832-68-0

Formula: C₁₂H₁₂N₆O₁₀S₂·2Na

Color and Shape: Neat

Molecular weight: 510.367

Ref: TR-C184745

Carumonam Sodium

CAS: 86832-68-0

Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.

Formula: C₁₂H₁₂N₆Na₂O₁₀S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 510.37

Ref: TM-T7723