CAS 86864-60-0

(2-bromoethoxy)-tert-butyldimethylsilane

Description:

(2-Bromoethoxy)-tert-butyldimethylsilane, with the CAS number 86864-60-0, is an organosilicon compound characterized by the presence of a tert-butyldimethylsilyl group and a bromoethoxy moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity due to the presence of the bromine atom, which can participate in nucleophilic substitution reactions. The tert-butyldimethylsilyl group serves as a protective group for alcohols and can enhance the compound's stability and solubility in organic solvents. Its structure allows for potential applications in organic synthesis, particularly in the formation of carbon-silicon bonds and as a reagent in various chemical transformations. Additionally, the compound's properties, such as boiling point and density, can vary based on purity and environmental conditions. Safety precautions should be taken when handling this substance, as it may pose health risks if inhaled or ingested, and appropriate personal protective equipment should be used.

Formula: C₈H₁₉BrOSi

InChI: InChI=1/C8H19BrOSi/c1-8(2,3)11(4,5)10-7-6-9/h6-7H2,1-5H3

SMILES: CC(C)(C)[Si](C)(C)OCCBr

Synonyms:

• (2-Bromoethoxy)(tert-butyl)dimethylsilane

(2-Bromoethoxy)-tert-butyldimethylsilane, 98%, stab. with sodium carbonate

CAS: 86864-60-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₉BrOSi

Purity: 98%

Color and Shape: Clear, Liquid

Molecular weight: 239.23

Ref: 02-H56594

(2-Bromoethoxy)(tert-butyl)dimethylsilane

CAS: 86864-60-0

Formula: C₈H₁₉BrOSi

Purity: 98%

Color and Shape: Liquid

Molecular weight: 239.2254

Ref: IN-DA0038DU

2-Bromoethoxy-t-butyl dimethylsilane

CAS: 86864-60-0

S02895 - 2-Bromoethoxy-t-butyl dimethylsilane

Formula: C₈H₁₉BrOSi

Purity: 95%

Color and Shape: Liquid

Molecular weight: 239.228

Ref: 10-S02895

(2-Bromoethoxy)-tert-butyldimethylsilane

CAS: 86864-60-0

Formula: C₈H₁₉BrOSi

Purity: >96.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 239.23

Ref: 3B-B4505

(2-Bromoethoxy)(tert-butyl)dimethylsilane

CAS: 86864-60-0

(2-Bromoethoxy)(tert-butyl)dimethylsilane

Formula: C₈H₁₉BrOSi

Purity: 96%

Color and Shape: clear. colourless liquid

Molecular weight: 239.23g/mol

Ref: 54-OR014998

(2-Bromoethoxy)-tert-butyldimethylsilane

Controlled Product

CAS: 86864-60-0

Applications (2-Bromoethoxy)-tert-butyldimethylsilane can be used in N-alkylation with 5-piperazin-1-yl-1H-indole to synthesize 5-(4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperazin-1-yl)-1H-indole.
References Johnson, M., et al.: J. Med. Chem., 55, 5828 (2012)

Formula: C₈H₁₉BrOSi

Color and Shape: Neat

Molecular weight: 239.225

Ref: TR-B686625

(2-Bromoethoxy)-tert-butyldimethylsilane

CAS: 86864-60-0

2-Bromoethoxy-tert-butyldimethylsilane is a conjugate that has been shown to have anticancer efficacy in vivo. It is a pyrimidine derivative and inhibits the viral enzyme RNA polymerase, thereby inhibiting viral replication. 2-Bromoethoxy-tert-butyldimethylsilane also inhibits glyceraldehyde 3-phosphate dehydrogenase, which is an enzyme that catalyzes the conversion of glucose into glyceraldehyde 3-phosphate and plays an important role in glycolysis. The compound has been shown to be active against mouse tumors, which are associated with endogenous retroviruses. The compound has also been shown to inhibit gapdh, an enzyme involved in energy metabolism and cancer therapy.

Formula: C₈H₁₉BrOSi

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 239.23 g/mol

Ref: 3D-FB76750