CAS 86867-01-8

S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride

Description:

S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride, commonly referred to as SAMe, is a naturally occurring compound involved in various biological processes, particularly in methylation reactions. It is a sulfonium compound derived from the amino acid L-methionine and adenosine triphosphate (ATP). SAMe plays a crucial role in the synthesis of neurotransmitters and is involved in the regulation of mood and liver function. As a chloride dihydrochloride salt, it is typically presented as a white to off-white crystalline powder, which is soluble in water. SAMe is known for its potential therapeutic applications, including the treatment of depression and osteoarthritis, due to its ability to influence methylation and support cellular processes. Its stability and bioavailability can be affected by factors such as pH and temperature. Additionally, SAMe is recognized for its antioxidant properties, contributing to cellular protection against oxidative stress. Overall, SAMe is a significant compound in both biochemistry and pharmacology, with ongoing research into its various health benefits.

Formula: C₁₅H₂₅Cl₃N₆O₄S

InChI: InChI=1S/C15H22N6O5S.3ClH/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;;;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);3*1H/t7-,8+,10+,11+,14+,27?;;;/m0.../s1

InChI key: KBAFOJZCBYWKPU-XQVUROGGSA-N

SMILES: C[S+](CC[C@@H](C(=O)O)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O.Cl.Cl.[Cl-]

Synonyms:

• [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium
• S-(5'-Adenosyl)-L-methionine chloride dihydrochloride >=75%
• SAM; ADOMET
• -methionine chloride dihydrochloride
• S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride
• S-(5'-Adenosyl)-L-methionine chloride (hydrochloride)
• -Adenosyl)-L-methionine chloride (hydrochloride)
• S-(5'-Adenosyl)-L-methionine chloride(SAM)
• -Adenosyl)-
• L
• SAM chloride dihydrochloride
• ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride

S-Adenosyl-L-methionine (chloride dihydrochloride)

CAS: 86867-01-8

S-Adenosyl-L-methionine (chloride dihydrochloride)

Formula: C₁₅H₂₅Cl₃N₆O₅S

Purity: 75%

Molecular weight: 507.82

Ref: 54-OR1006408

S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride

CAS: 86867-01-8

Formula: C₁₅H₂₅Cl₃N₆O₅S

Purity: 75%

Color and Shape: Solid

Molecular weight: 507.8202

Ref: IN-DA00H150

S-Adenosyl-L-methionine chloride 2HCl

CAS: 86867-01-8

((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride

Formula: C₁₅H₂₅Cl₃N₆O₅S

Purity: 75%

Molecular weight: 507.82

Ref: IN-DG377203

S-(5'-Adenosyl)-L-methionine chloride dihydrochloride

CAS: 86867-01-8

S-adenosyl-L-methionine chloride dihydrochloride is a form of S-adenosyl-L-methionine. It is used as a nutritional supplement and has been shown to increase the production of antibodies in the body. This drug is also used for the treatment of inflammatory diseases, such as rheumatoid arthritis and osteoarthritis, because it inhibits cyclooxygenase enzymes. S-adenosyl-L-methionine chloride dihydrochloride binds to the response element on DNA that regulates gene expression and inhibits polymerase chain reactions by blocking the binding of nucleic acids to their complementary strands. The mechanism of action of this drug has not been established but may be related to its ability to inhibit nuclear DNA transcription or cell proliferation by affecting camp concentration.

Formula: C₁₅H₂₃ClN₆O₅S·2HCl

Purity: Min. 75 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 507.82 g/mol

Ref: 3D-NA29499

((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride

CAS: 86867-01-8

Purity: 75%

Color and Shape: Solid

Molecular weight: 507.8099976

Ref: 10-F869710

S-Adenosyl-L-methionine chloride dihydrochloride

CAS: 86867-01-8

S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride functions as a methyl donor and cofactor.

Formula: C₁₅H₂₅Cl₃N₆O₅S

Color and Shape: Solid

Molecular weight: 507.81

Ref: TM-TN11105