CAS 86891-15-8

(8alpha,10xi)-6-prop-2-en-1-ylergoline-8-carboxylic acid

Description:

The chemical substance known as (8alpha,10xi)-6-prop-2-en-1-ylergoline-8-carboxylic acid, with the CAS number 86891-15-8, is a member of the ergoline family, which is characterized by a tetracyclic structure derived from the ergot alkaloids. This compound features a carboxylic acid functional group, which contributes to its acidic properties and potential reactivity. The presence of a prop-2-en-1-yl group indicates that it has an unsaturated side chain, which may influence its biological activity and interactions. Ergoline derivatives are often studied for their pharmacological properties, including effects on neurotransmitter systems. The specific stereochemistry denoted by the (8alpha,10xi) configuration suggests unique spatial arrangements that can significantly affect the compound's biological behavior and receptor binding affinity. Overall, this compound's structural features may render it of interest in medicinal chemistry and pharmacology, particularly in the context of neuroactive compounds.

Formula: C₁₈H₂₀N₂O₂

InChI: InChI=1/C18H20N2O2/c1-2-6-20-10-12(18(21)22)7-14-13-4-3-5-15-17(13)11(9-19-15)8-16(14)20/h2-5,9,12,14,16,19H,1,6-8,10H2,(H,21,22)/t12-,14?,16+/m0/s1

Synonyms:

• 6-Allyldihydronorisolysergic Acid
• Ergoline-8-carboxylic acid, 6-(2-propenyl)-, (8-alpha)-
• Cabergoline Impurity 10
• Ergoline-8-carboxylic acid, 6-(2-propenyl)-, (8α)- (9CI)

6-Allyldihydronorisolysergic Acid

Controlled Product

CAS: 86891-15-8

Applications 6-Allyldihydronorisolysergic Acid is an intermediate in the synthesis of the S-isomer of Cabergoline (C050000), a dopamine D2-receptor agonist.
References Cerny, A., et al.: Collect. Czech. Chem. Commun., 48, 1483 (1983);

Formula: C₁₈H₂₀N₂O₂

Color and Shape: Neat

Molecular weight: 296.36

Ref: TR-A549625