CAS 869113-09-7
:Umeclidinium bromide
Description:
Umeclidinium bromide is a synthetic, long-acting muscarinic antagonist (LAMA) primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It functions by inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to bronchodilation and improved airflow. This compound is characterized by its quaternary ammonium structure, which contributes to its pharmacological properties and solubility in water. Umeclidinium bromide is typically administered via inhalation, allowing for targeted delivery to the lungs while minimizing systemic side effects. Its long duration of action allows for once-daily dosing, enhancing patient compliance. The substance is generally well-tolerated, with common side effects including dry mouth and potential cardiovascular effects. As a member of the anticholinergic class, it is important for patients to be monitored for any adverse reactions, especially those with pre-existing conditions. Overall, umeclidinium bromide represents a significant advancement in the treatment of respiratory diseases, providing effective symptom relief for patients.
Formula:C29H34NO2·Br
InChI:InChI=1S/C29H34NO2.BrH/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25;/h1-15,31H,16-24H2;1H/q+1;/p-1
InChI key:InChIKey=PEJHHXHHNGORMP-UHFFFAOYSA-M
SMILES:C(O)(C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2)(C4=CC=CC=C4)C5=CC=CC=C5.[Br-]
Synonyms:- 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-, bromide
- 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-, bromide (1:1)
- 4-(Hydroxydiphenylmethyl)-1-[2-[(phenylmethyl)oxy]ethyl]-1-azabicyclo[2.2.2]octanium bromide
- 4-[Hydroxy(diphenyl)methyl]-1-[2-[(phenylmethyl)oxy]ethyl]-1-azoniabicyclo[2.2.2]octane bromide
- Ellipta
- Incruse Ellipta
- Jmechlidinium bromide
- Rolufta Ellipta
- Umeclidinium bromide
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Found 11 products.
Umeclidinium Bromide
CAS:Formula:C29H34NO2·BrColor and Shape:White To Off-White SolidMolecular weight:428.60 79.90Umeclidinium Bromide
CAS:Controlled ProductFormula:C29H34NO2·BrColor and Shape:NeatMolecular weight:508.49Umeclidinium bromide
CAS:<p>Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.</p>Formula:C29H34BrNO2Purity:98.4% - 99.89%Color and Shape:SolidMolecular weight:508.49Umeclidinium Bromide
CAS:Controlled Product<p>Applications Umeclidinium Bromide is considered as a potentially long-acting antimuscarinic agent.<br>References Cazzola, M., et al.: Pharmacol., Rev., 64, 450 (2012); Laine, D., et al.: J. Med. Chem., 52, 2493 (2009)<br></p>Formula:C29H34NO2·BrColor and Shape:WhiteMolecular weight:508.49Umeclidinium Bromide-d5
CAS:Controlled ProductFormula:C29D5H29NO2·BrColor and Shape:NeatMolecular weight:513.521Umeclidinium Bromide-d10
CAS:Controlled Product<p>Applications Umeclidinium Bromide-d10 is the isotope labelled analog of Umeclidinium Bromide (U710000); a compound that is considered as a potentially long-acting antimuscarinic agent.<br>References Cazzola, M., et al.: Pharmacol., Rev., 64, 450 (2012); Laine, D., et al.: J. Med. Chem., 52, 2493 (2009)<br></p>Formula:C29H24D10BrNO2Color and Shape:NeatMolecular weight:518.55Umeclinidium bromide
CAS:<p>Antagonist of mACh receptors</p>Formula:C29H34BrNO2Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:508.49 g/mol
