Demethylolivomycin A is a natural antibiotic compound that belongs to the class of anthracycline antibiotics, which are known for their potent antitumor activity. It is derived from the fermentation of certain Streptomyces species. The chemical structure of demethylolivomycin A features a complex polycyclic ring system, which is characteristic of anthracyclines, and includes multiple hydroxyl groups that contribute to its biological activity. This compound exhibits a range of pharmacological properties, including the ability to intercalate DNA, which disrupts the replication process in rapidly dividing cells, making it a candidate for cancer treatment. Additionally, demethylolivomycin A has shown activity against various bacterial strains, indicating its potential as an antibiotic. Its mechanism of action involves the generation of reactive oxygen species, leading to oxidative stress in target cells. However, like many anthracyclines, it may also exhibit dose-dependent toxicity, particularly to cardiac tissues. Research continues to explore its therapeutic potential and the optimization of its use in clinical settings.

demethylolivomycin A

86917-61-5: Demethylolivomycin A is a natural antibiotic compound that belongs to the class of anthracycline antibiotics, which are known for their potent antitumor activity. It is derived from the fermentation of certain Streptomyces species. The chemical structure of demethylolivomycin A features a complex polycyclic ring system, which is characteristic of anthracyclines, and includes multiple hydroxyl groups that contribute to its biological activity. This compound exhibits a range of pharmacological properties, including the ability to intercalate DNA, which disrupts the replication process in rapidly dividing cells, making it a candidate for cancer treatment. Additionally, demethylolivomycin A has shown activity against various bacterial strains, indicating its potential as an antibiotic. Its mechanism of action involves the generation of reactive oxygen species, leading to oxidative stress in target cells. However, like many anthracyclines, it may also exhibit dose-dependent toxicity, particularly to cardiac tissues. Research continues to explore its therapeutic potential and the optimization of its use in clinical settings.

Demethylolivomycin A is an antitumor antibiotic with activity against Gram-positive bacteria and demonstrates effectiveness against leukemia P388.

CAS 86917-61-5

demethylolivomycin A

Demethylolivomycin A

Ref: TM-TN10757