CAS: 869288-64-2 - 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone

Formula: C₂₂H₂₀F₃N₅O₃S

InChI: InChI=1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30)

InChI key: InChIKey=HESLKTSGTIBHJU-UHFFFAOYSA-N

SMILES: O=C1NC2=CC=C(C=C2CC1)NC3=NC=C(C(=N3)NCC4=CC=CC(=C4)S(=O)(=O)C)C(F)(F)F

Synonyms:

• 2(1H)-Quinolinone, 3,4-dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-
• PF 573228
• 6-[(4-((3-(Methanesulfonyl)benzyl)amino)-5-trifluoromethylpyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one
• 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone

3,4-DIHYDRO-6-[[4-[[[3-(METHYLSULFONYL)PHENYL]METHYL]AMINO]-5-(TRIFLUOROMETHYL)-PYRIMIDIN-2-YL]AMINO]-2(1H)-QUINOLINONE

CAS: 869288-64-2

• Formula: C₂₂H₂₀F₃N₅O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 491.4861

PF-573228

CAS: 869288-64-2

• Formula: C₂₂H₂₀F₃N₅O₃S
• Molecular weight: 491.49

PF-573228

CAS: 869288-64-2

• Formula: C₂₂H₂₀F₃N₅O₃S
• Molecular weight: 491.49

PF-573228

CAS: 869288-64-2

PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is …

• Formula: C₂₂H₂₀F₃N₅O₃S
• Purity: 96.58% - 98.86%
• Color and Shape: Solid
• Molecular weight: 491.49

PF 573228

CAS: 869288-64-2

Inhibitor of FAK kinase

• Formula: C₂₂H₂₀F₃N₅O₃S
• Purity: 98%
• Molecular weight: 491.49 g/mol