CAS 869490-23-3
:Gosogliptin
Description:
Gosogliptin is a pharmaceutical compound classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, primarily used in the management of type 2 diabetes mellitus. It functions by enhancing the levels of incretin hormones, which in turn increases insulin secretion and decreases glucagon release in a glucose-dependent manner, thereby helping to regulate blood sugar levels. Gosogliptin is characterized by its selective inhibition of the DPP-4 enzyme, which plays a crucial role in glucose metabolism. The compound is typically administered orally and is often used in combination with other antidiabetic medications to improve glycemic control. Its chemical structure includes specific functional groups that contribute to its pharmacological activity and stability. As with other DPP-4 inhibitors, common side effects may include gastrointestinal disturbances and potential risk of infections. Overall, gosogliptin represents a valuable option in diabetes therapy, offering a mechanism that aligns with the physiological regulation of glucose homeostasis.
Formula:C17H24F2N6O
InChI:InChI=1S/C17H24F2N6O/c18-17(19)2-5-25(12-17)15(26)14-10-13(11-22-14)23-6-8-24(9-7-23)16-20-3-1-4-21-16/h1,3-4,13-14,22H,2,5-12H2/t13-,14-/m0/s1
InChI key:InChIKey=QWEWGXUTRTXFRF-KBPBESRZSA-N
SMILES:C(=O)([C@@H]1C[C@@H](CN1)N2CCN(CC2)C=3N=CC=CN3)N4CC(F)(F)CC4
Synonyms:- PF 734200
- (3,3-Difluoropyrrolidin-1-yl)[(2S,4S)-4-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrrolidin-2-yl]methanone
- Pyrrolidine, 3,3-difluoro-1-[[(2S,4S)-4-[4-(2-pyrimidinyl)-1-piperazinyl]-2-pyrrolidinyl]carbonyl]-
- (3,3-Difluoro-1-pyrrolidinyl)[(2S,4S)-4-[4-(2-pyrimidinyl)-1-piperazinyl]-2-pyrrolidinyl]methanone
- Methanone, (3,3-difluoro-1-pyrrolidinyl)[(2S,4S)-4-[4-(2-pyrimidinyl)-1-piperazinyl]-2-pyrrolidinyl]-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.
Gosogliptin
CAS:<p>Gosogliptin is a potent, orally active, highly selective, reversible and competitive inhibitor of DPP-4, increasing the level of intestinal GLP-1 and GIP.</p>Formula:C17H24F2N6OPurity:99.74%Color and Shape:SolidMolecular weight:366.41
