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CAS 86954-05-4

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Cbz-DL-Prolinol

Description:
Cbz-DL-Prolinol, also known as carbobenzyloxy-DL-prolinol, is an amino alcohol that serves as an important intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and biologically active compounds. It features a proline backbone, which is a cyclic amino acid, and is protected by a carbobenzyloxy (Cbz) group, enhancing its stability and reactivity. The compound is typically a white to off-white solid and is soluble in polar organic solvents such as methanol and ethanol, but less soluble in non-polar solvents. Cbz-DL-Prolinol exhibits characteristics typical of amino alcohols, including the ability to participate in hydrogen bonding and act as a chiral auxiliary in asymmetric synthesis. Its structure allows for the formation of various derivatives, making it versatile in synthetic chemistry. Additionally, the presence of both an amine and an alcohol functional group enables it to engage in a range of chemical reactions, including nucleophilic substitutions and coupling reactions, which are valuable in the development of complex organic molecules.
Synonyms:
  • 2-Hydroxymethyl-pyrrolidine-1-carboxylic acid benzyl ester
  • Benzyl 2-(Hydroxymethyl)Pyrrolidine-1-Carboxylate
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