CAS 86976-77-4

2'-deoxy-5-fluoro-5'-O-[hydroxy(tetradecyloxy)phosphoryl]uridine

Description:

2'-Deoxy-5-fluoro-5'-O-[hydroxy(tetradecyloxy)phosphoryl]uridine, with CAS number 86976-77-4, is a modified nucleoside that incorporates a fluorine atom at the 5-position of the uridine base, which can influence its biological activity and stability. This compound features a tetradecyloxy group attached to the phosphate moiety, enhancing its lipophilicity and potentially facilitating cellular uptake. The presence of the deoxy group indicates that it lacks an oxygen atom at the 2' position of the ribose sugar, which is characteristic of DNA nucleosides. The hydroxy(tetradecyloxy)phosphoryl group suggests that it may be involved in various biochemical applications, possibly as a prodrug or in gene therapy contexts. Overall, this compound's unique structural features may contribute to its utility in research and therapeutic applications, particularly in the fields of molecular biology and medicinal chemistry. Its specific interactions and efficacy would depend on further empirical studies.

Formula: C₂₃H₄₀FN₂O₈P

InChI: InChI=1/C23H40FN2O8P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-32-35(30,31)33-17-20-19(27)15-21(34-20)26-16-18(24)22(28)25-23(26)29/h16,19-21,27H,2-15,17H2,1H3,(H,30,31)(H,25,28,29)/t19-,20+,21-/m0/s1