CAS 87-11-6

Thiolutin

Description:

Thiolutin, with the CAS number 87-11-6, is a chemical compound known for its role as a biological and biochemical reagent. It is classified as a thiazole derivative and is recognized for its ability to inhibit certain enzymes, particularly those involved in the biosynthesis of nucleic acids. Thiolutin exhibits a yellow crystalline appearance and is soluble in organic solvents, making it useful in various laboratory applications. Its structure includes a thiol group, which contributes to its reactivity and biological activity. In research, thiolutin has been utilized to study cellular processes and has shown potential in antimicrobial and anticancer activities. However, it is important to handle thiolutin with care, as it may pose health risks, including skin and respiratory irritation. Proper safety protocols should be followed when working with this compound in a laboratory setting. Overall, thiolutin serves as a valuable tool in biochemical research, particularly in the study of enzyme inhibition and cellular metabolism.

Formula: C₈H₈N₂O₂S₂

InChI: InChI=1/C8H8N2O2S2/c1-4(11)9-6-7-5(3-13-14-7)10(2)8(6)12/h3H,1-2H3,(H,9,11)

InChI key: InChIKey=MHMRAFONCSQAIA-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=C2C(N(C)C1=O)=CSS2

Synonyms:

• 1,2-Dithiolo[4,3-b]pyrrol-5(4H)-one, 6-acetamido-4-methyl-
• 1,2-Dithiolo[4,3-b]pyrrole, acetamide deriv.
• 3-Acetamido-5-methylpyrrolin-4-one[4,3-d]-1,2-dithiole
• 6-Acetamido-4-Methyl-1,2-Dithiolo[4,3-B]Pyrrol-5-One
• Acetamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-
• Acetopyrrothin
• N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide
• N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
• NSC 3927
• N-(5-keto-4-methyl-dithiolo[4,3-b]pyrrol-6-yl)acetamide
• THIOLUTIN
• acetopyrrothine
• N-acetylpyrrothine, Farcinicine, Acetopyrrothine
• N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
• 6-acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4h)-one
• Thiolutin from Streptomyces luteosporeus
• 6-(acetylamino)-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4h)-one
• 4-Methyl-6-(acetylamino)-4,5-dihydro-1,2-dithiolo[4,3-b]pyrrole-5-one
• N-(4-methyl-5-oxo-[1,2]dithiolo[4,3-b]pyrrol-6-yl)ethanamide
• Thiolutin ,80%
• T-00098
• Thiolutin NSC 3927
• 4-Methyl-6-(acetylamino)-1,2-dithiolo[4,3-b]pyrrole-5(4H)-one
• Aureothricin, Farcinicin, Propiopyvothine
• THIOLUTIN (ACETOPYRROTHIN)
• THIOLUTIN USP/EP/BP
• 6-acetamido-4-methyl-2-dithiolo(4.3-b)pyrrol-5(4h)-one

Thiolutin

CAS: 87-11-6

Thiolutin (Acetopyrrothin), from Streptomyces, inhibits endothelial adhesion, has antibiotic and anti-angiogenic effects, and phosphorylates Hsp27.

Formula: C₈H₈N₂O₂S₂

Purity: 98.00% - >99.99%

Color and Shape: Solid

Molecular weight: 228.29

Ref: TM-T67708

Thiolutin

CAS: 87-11-6

Thiolutin

Purity: ≥98%

Molecular weight: 228.29g/mol

Ref: 54-BUP02525

Thiolutin from Streptomyces luteosporeus

CAS: 87-11-6

Thiolutin from Streptomyces luteosporeus

Formula: C₈H₈N₂O₂S₂

Purity: By hplc: 98.97% (Typical Value in Batch COA)

Color and Shape: yellow powder

Molecular weight: 228.29g/mol

Ref: 54-BIT1001

Thiolutin

CAS: 87-11-6

Formula: C₈H₈N₂O₂S₂

Purity: ≥ 95.0%

Color and Shape: Yellow powder or solid

Molecular weight: 228.29

Ref: 7W-GA0837

Thiolutin

CAS: 87-11-6

Inhibitor of RNA polymerases; inhibitor of HSP27-cytoskeleton interactions

Formula: C₈H₈N₂O₂S₂

Purity: Min. 80 Area-%

Color and Shape: Yellow Powder

Molecular weight: 228.29 g/mol

Ref: 3D-AT02783

Thiolutin

CAS: 87-11-6

Purity: ≥95%

Molecular weight: 228.2799988

Ref: 10-F951531