CAS 87-42-3

6-Chloropurine

Description:

6-Chloropurine is a purine derivative characterized by the presence of a chlorine atom at the 6-position of the purine ring. Its molecular formula is C5H4ClN5, and it has a molecular weight of approximately 173.57 g/mol. This compound appears as a white to off-white crystalline solid and is soluble in water and organic solvents such as dimethyl sulfoxide (DMSO). 6-Chloropurine is primarily known for its role as a nucleobase analog, which can interfere with nucleic acid synthesis and has applications in research and medicinal chemistry, particularly in the development of antiviral and anticancer agents. It can act as a purine antagonist, inhibiting the activity of enzymes involved in nucleotide metabolism. Additionally, due to its structural similarity to adenine and guanine, it can be incorporated into RNA and DNA, potentially leading to mutagenic effects. Safety precautions should be taken when handling this compound, as it may pose health risks, including potential carcinogenicity.

Formula: C₅H₃ClN₄

InChI: InChI=1/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-3H

InChI key: InChIKey=ZKBQDFAWXLTYKS-UHFFFAOYSA-N

SMILES: ClC1=C2C(=NC=N1)N=CN2

Synonyms:

• 6-Cp
• 6-Chloropurine
• Akos Bbs-00002143
• 1H-Purine, 6-chloro-
• 6-Chloro-1H-purine
• 6-Chloro-7H-purine
• 6-Chloro-9H-purine
• 6-Chlorpurin
• 6-Cloropurina
• 9H-Purine, 6-chloro-
• Nsc 744
• Purine, 6-chloro-
• 6-chloro-1h-purin
• SK 6048
• X 47
• TIMTEC-BB SBB004030
• ClP
• x47
• sk6048
• CHLOROPURINE, 6-
• 6-chloro-purin
• nsc744

6-Chloropurine

CAS: 87-42-3

Formula: C₅H₃ClN₄

Purity: >98.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 154.56

Ref: 3B-C0278

6-Chloropurine, 99%

CAS: 87-42-3

6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some d

Formula: C₅H₃ClN₄

Purity: 99%

Color and Shape: Powder, White or yellow to pale brown

Molecular weight: 154.56

Ref: 02-A11202

6-Chloropurine

CAS: 87-42-3

Formula: C₅H₃ClN₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 154.5571

Ref: IN-DA0034CS

6-Chloropurine

CAS: 87-42-3

6-Chloropurine

Purity: ≥98%

Molecular weight: 154.56g/mol

Ref: 54-BUP19457

6-Chloro-9H-purine

CAS: 87-42-3

6-Chloro-9H-purine

Formula: C₅H₃ClN₄

Purity: 98%

Color and Shape: faint yellow to faint beige powder

Molecular weight: 154.56g/mol

Ref: 54-OR11255

6-Chloropurine

CAS: 87-42-3

Formula: C₅H₃ClN₄

Molecular weight: 154.56

Ref: 7W-GK1105

6-Chloropurine

CAS: 87-42-3

Formula: C₅H₃ClN₄

Molecular weight: 154.56

Ref: 4Z-P-185013

6-Chloropurine

CAS: 87-42-3

6-Chloropurine (6-Chloro-9H-purine) is a building block in chemical synthesis,with Antitumor activities.

Formula: C₅H₃ClN₄

Purity: 99.5%

Color and Shape: Light Yellow Powder

Molecular weight: 154.56

Ref: TM-T7470

6-Chloropurine

CAS: 87-42-3

6-Chloropurine is an isothiouronium salt that is metabolized by the enzyme thiopurine methyltransferase to its active form, 6-methylthioinosine. It has been shown to inhibit the growth of bacterial cells in culture by binding to their adenine nucleotide. 6-Chloropurine inhibits the synthesis of purines and pyrimidines, which are involved in DNA replication and RNA synthesis. 6-Chloropurine has been shown to have cytotoxic effects on certain human carcinoma cell lines and may be used as a chemotherapeutic agent for these types of cancer. The drug has also been shown to have high values with aerobacter aerogenes, which is a bacterium that can cause lung infections.

Formula: C₅H₃ClN₄

Purity: Min. 99 Area-%

Color and Shape: Yellow Powder

Molecular weight: 154.56 g/mol

Ref: 3D-FC06554

6-Chloropurine

CAS: 87-42-3

Formula: C₅H₃ClN₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 154.56

Ref: 10-F032518

6-Chloropurine extrapure, 99%

CAS: 87-42-3

Formula: C₅H₃ClN₄

Purity: min. 99%

Color and Shape: Pale yellow, Crystalline powder, Clear

Molecular weight: 154.56

Ref: SR-62020

6-Chloropurine

Controlled Product

CAS: 87-42-3

Formula: C₅H₃ClN₄

Color and Shape: Neat

Molecular weight: 154.56

Ref: TR-C379850