CAS 870153-29-0

1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-3-hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy- (9CI)

Description:

1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-3-hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy- (9CI), with CAS number 870153-29-0, is a complex organic compound characterized by its indole core structure, which is known for its presence in various biologically active molecules. This compound features multiple functional groups, including a carboxamide and methoxy group, contributing to its potential biological activity. The stereochemistry indicated by the (1S) and (3S) designations suggests specific spatial arrangements of atoms, which can significantly influence the compound's interactions with biological targets. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the pyrrolidine ring and hydroxyl group may enhance its solubility and bioavailability. Overall, this compound exemplifies the complexity and diversity of organic molecules used in drug discovery and development, highlighting the importance of structural features in determining biological activity.

Formula: C₂₄H₃₂N₄O₆

Synonyms:

• 1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-3-hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy- (9CI)
• PF-00835231

PF-00835231

CAS: 870153-29-0

Formula: C₂₄H₃₂N₄O₆

Purity: 95%

Molecular weight: 472.5341

Ref: IN-DA01V7H3

PF-00835231

CAS: 870153-29-0

PF-00835231

Purity: ≥95%

Molecular weight: 472.53g/mol

Ref: 54-BUP03286

PF-00835231

CAS: 870153-29-0

PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-

Formula: C₂₄H₃₂N₄O₆

Purity: 97.83%

Color and Shape: Solid

Molecular weight: 472.53

Ref: TM-T9458

PF 00835231

CAS: 870153-29-0

PF 00835231 is an investigational viral polymerase inhibitor, which is derived from the structural optimization of existing antiviral compounds. This small molecule manifests its mechanism of action by directly inhibiting the activity of the viral RNA-dependent RNA polymerase, a crucial enzyme in the replication machinery of coronaviruses. By binding to the active site of the polymerase, PF 00835231 effectively obstructs the replication process of viral RNA, thereby limiting viral proliferation within the host.

Formula: C₂₄H₃₂N₄O₆

Purity: Min. 98 Area-%

Color and Shape: Slightly Yellow Powder

Molecular weight: 472.53 g/mol

Ref: 3D-BP180196