CAS: 870281-86-0 - 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone

Formula: C₁₇H₁₆FN₃O

InChI: InChI=1S/C17H16FN3O/c1-2-13(19)16-20-14-10-6-9-12(18)15(14)17(22)21(16)11-7-4-3-5-8-11/h3-10,13H,2,19H2,1H3/t13-/m0/s1

InChI key: InChIKey=BNMGOWXQUZHWIO-ZDUSSCGKSA-N

SMILES: O=C1C=2C(F)=CC=CC2N=C(N1C=3C=CC=CC3)C(N)CC

Synonyms:

• (S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propan-1-amine
• (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
• 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenylquinazolin-4-one
• 4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

CAS: 870281-86-0

• Formula: C₁₇H₁₆FN₃O
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 297.3268

Idelalisib Impurity 5

CAS: 870281-86-0

• Formula: C₁₇H₁₆FN₃O
• Color and Shape: Off-White Solid
• Molecular weight: 297.33

2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone

CAS: 870281-86-0

Applications 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation …

• Formula: C₁₇H₁₆FN₃O
• Color and Shape: Neat
• Molecular weight: 297.33

2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone

CAS: 870281-86-0

Intermediate in the synthesis of idelalisib (CAL 101)

• Formula: C₁₇H₁₆FN₃O
• Purity: Min. 95%
• Molecular weight: 297.33 g/mol