CAS 870483-87-7

GW2580

Description:

GW2580 is a small molecule inhibitor primarily known for its role as a selective antagonist of the colony-stimulating factor 1 receptor (CSF1R). This compound has garnered attention in the field of cancer research and immunology due to its potential to modulate the tumor microenvironment by inhibiting macrophage recruitment and activation. GW2580 is characterized by its ability to interfere with CSF1 signaling pathways, which are crucial for the survival and proliferation of macrophages. The compound is typically studied in preclinical models to evaluate its efficacy in various cancer types and inflammatory diseases. In terms of its chemical properties, GW2580 is a synthetic compound with a specific molecular structure that allows it to bind selectively to CSF1R, thereby blocking its activity. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion (ADME) profiles, are also important considerations in its development as a therapeutic agent. Overall, GW2580 represents a promising avenue for targeted therapies aimed at modulating immune responses in disease contexts.

GW 2580

CAS: 870483-87-7

Formula: C₂₀H₂₂N₄O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 366.42

Ref: 3B-G0504

GW2580

CAS: 870483-87-7

Formula: C₂₀H₂₂N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 366.4137

Ref: IN-DA0036CW

GW2580

CAS: 870483-87-7

GW2580

Purity: 98%

Molecular weight: 366.41g/mol

Ref: 54-OR1026540

GW2580

CAS: 870483-87-7

GW2580

Purity: ≥98%

Molecular weight: 366.41g/mol

Ref: 54-BUP15491

GW2580

CAS: 870483-87-7

GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.

Formula: C₂₀H₂₂N₄O₃

Purity: 99.48% - >99.99%

Color and Shape: Solid

Molecular weight: 366.41

Ref: TM-T2659

GW 2580-d3

Controlled Product

CAS: 870483-87-7

Formula: C₂₀D₆H₁₆N₄O₃

Color and Shape: Neat

Molecular weight: 372.451

Ref: TR-G931007

5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine

CAS: 870483-87-7

5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine is a monoclonal antibody that blocks the signal of CTLA-4, a receptor on T cells. It has been shown to be effective in inhibiting skin cancer and primary breast cancers. This drug also has immunomodulatory effects and can be used to treat autoimmune diseases. 5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine binds to ctla-4 with high affinity and specificity, preventing the interaction of ctla-4 with its ligands such as CD80 (B7.1) and CD86 (B7.2). This prevents the activation of T cells by antigen presenting cells and suppresses the immune response.

Formula: C₂₀H₂₂N₄O₃

Purity: Min. 95%

Molecular weight: 366.41 g/mol

Ref: 3D-FM31223