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CAS 87056-78-8

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Quinagolide

Description:
Quinagolide is a synthetic compound primarily used as a dopamine agonist, specifically targeting the D2 dopamine receptor. It is characterized by its ability to inhibit prolactin secretion, making it useful in the treatment of conditions such as hyperprolactinemia and certain types of pituitary tumors. Quinagolide is typically administered orally and is known for its relatively selective action, which minimizes side effects associated with broader dopamine receptor activation. The compound has a moderate molecular weight and exhibits lipophilic properties, allowing for effective absorption and distribution in the body. Its pharmacokinetics involve hepatic metabolism, and it is primarily excreted through the urine. As with many pharmacological agents, monitoring for potential side effects, including nausea, dizziness, and fatigue, is essential during treatment. Overall, Quinagolide represents an important therapeutic option in endocrinology, particularly for managing disorders related to prolactin dysregulation.
Formula:C20H33N3O3S
InChI:InChI=1/C20H33N3O3S/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3/t16-,17+,19-/s2
InChI key:InChIKey=GDFGTRDCCWFXTG-NZYAKQSMNA-N
SMILES:C(CC)N1[C@]2([C@@](CC=3C(C2)=CC=CC3O)(C[C@H](NS(N(CC)CC)(=O)=O)C1)[H])[H]
Synonyms:
  • Benzo[g]quinoline, sulfamide deriv.
  • Cv 205-502
  • N,N-diethyl-N'-(6-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-3-yl)sulfuric diamide
  • N,N-diethyl-N'-[(3S,4aS,10aR)-6-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-3-yl]sulfamide
  • Norprolac
  • Sdz 205-502
  • Sulfamide, N,N-diethyl-N′-(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)-, (3R,4aR,10aS)-rel-
  • Sulfamide, N,N-diethyl-N′-(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)-, (3α,4aα,10aβ)-
  • Sulfamide, N,N-diethyl-N′-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]-, rel-
  • rel-N,N-Diethyl-N′-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfamide
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