CAS: 87081-35-4 - Leptomycin B

Formula: C₃₃H₄₈O₆

InChI: InChI=1S/C33H48O6/c1-9-28(14-15-29-24(5)13-16-31(36)39-29)19-22(3)12-10-11-21(2)17-25(6)32(37)27(8)33(38)26(7)18-23(4)20-30(34)35/h10-11,13-17,19-20,22,24-27,29,33,38H,9,12,18H2,1-8H3,(H,34,35)/b11-10+,15-14+,21-17+,23-20+,28-19-/t22-,24+,25-,26+,27-,29+,33-/m1/s1

InChI key: InChIKey=YACHGFWEQXFSBS-XYERBDPFSA-N

SMILES: O=C(O)C=C(C)CC(C)C(O)C(C(=O)C(C=C(C=CCC(C=C(C=CC1OC(=O)C=CC1C)CC)C)C)C)C

Synonyms:

• (2E,10E,12E,16E,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid
• (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2R,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid
• (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid
• (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid
• 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-
• 2,10,12,16,18-Nonadecapentaenoic acid, 19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-, (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-
• 2,10,12,16,18-Nonadecapentanoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-
• Antibiotic CI 940
• Antibiotic CL 1957A
• Ci-940
• Cl 1957A
• Elactocin
• Mantuamycin
• Nsc 364372
• Pd 114720
• Leptomycin B

Leptomycin B

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Purity: 97.6%
• Color and Shape: Colorless ethanolic solution
• Molecular weight: 541.0

LEPTOMYCIN B FROM STREPTOMYCES SP

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 540.7306

Leptomycin B

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Molecular weight: 540.73

Leptomycin B

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Purity: By hplc: 98.13% (Typical Value in Batch COA)
• Color and Shape: colourless liquid
• Molecular weight: 540.73g/mol

Leptomycin B

CAS: 87081-35-4

Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.

• Formula: C₃₃H₄₈O₆
• Purity: 99.04% - 99.71%
• Color and Shape: White Crystalline Solid
• Molecular weight: 540.73

Leptomycin B, Streptomyces sp. ATS1287

CAS: 87081-35-4

• Purity: 95%
• Color and Shape: Liquid
• Molecular weight: 540.7410278320312

Leptomycin B (5 μg/mL in Ethanol)

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Color and Shape: Single Solution
• Molecular weight: 540.73

Leptomycin B

CAS: 87081-35-4

• Formula: C₃₃H₄₈O₆
• Color and Shape: Neat
• Molecular weight: 540.73

Leptomycin B

CAS: 87081-35-4

Leptomycin B is a protein kinase inhibitor that binds to the ATP-binding site of the …

• Purity: Min. 95%