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CAS 87084-47-7

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chimeramycin A

Description:
Chimeramycin A is a natural product belonging to the class of antibiotics known as anthracyclines, which are characterized by their complex polycyclic structures and ability to intercalate DNA. It is produced by certain strains of the bacterium *Streptomyces chrysomallus*. Chimeramycin A exhibits potent antibacterial and antitumor activities, making it of interest in pharmaceutical research. Its mechanism of action primarily involves the inhibition of DNA synthesis, which is crucial for cell division and proliferation. The compound is known for its unique structural features, including a sugar moiety and a chromophore that contribute to its biological activity. Additionally, chimeramycin A has been studied for its potential use in cancer therapy due to its ability to target rapidly dividing cells. However, like many antibiotics, its use may be limited by issues of resistance and toxicity, necessitating further research to optimize its therapeutic applications. Overall, chimeramycin A represents a significant area of study in the development of new antimicrobial and anticancer agents.
Formula:C48H82N2O14
InChI:InChI=1/C47H80N2O14/c1-15-35-26(3)20-25(2)16-18-36(61-39-19-17-34(48(11)12)29(6)56-39)27(4)21-33(24-50)43(28(5)37(59-32(9)51)22-38(52)60-35)63-46-42(53)41(49(13)14)44(30(7)58-46)62-40-23-47(10,55)45(54)31(8)57-40/h16,18,20,24,26-31,33-37,39-46,53-55H,15,17,19,21-23H2,1-14H3/b18-16+,25-20+/t26-,27+,28-,29+,30+,31-,33+,34-,35+,36?,37+,39-,40-,41+,42+,43+,44+,45-,46-,47+/m0/s1
Synonyms:
  • (9R)-23-De[(6-deoxy-2-O,3-O-dimethyl-β-D-allopyranosyl)oxy]-9-deoxo-9-[[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]tyrosine [antibiotic]3-acetate
  • chimeramycin A
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