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CAS 871038-72-1

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Raltegravir potassium

Description:
Raltegravir potassium is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of drugs known as integrase inhibitors, which work by blocking the integrase enzyme, thereby preventing the integration of viral DNA into the host cell's genome. This action helps to inhibit viral replication. Raltegravir is characterized by its relatively low molecular weight and a specific chemical structure that includes a pyrimidinone core. It is typically administered orally and is known for its favorable pharmacokinetic profile, including good bioavailability and a manageable side effect profile. The drug is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance development. Raltegravir potassium is soluble in water, which facilitates its formulation in various dosage forms. As with any medication, it is essential to monitor for potential drug interactions and side effects, and it is contraindicated in certain populations, making medical supervision crucial during treatment.
Formula:C20H20FKN6O5
InChI:InChI=1/C20H21FN6O5.K/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11;/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30);/q;+1/p-1
SMILES:Cc1nnc(C(=O)NC(C)(C)c2nc(c(c(=O)n2C)O)C(=NCc2ccc(cc2)F)O)o1.K
Synonyms:
  • N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide potassium salt
  • Mk 0518
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