CAS 87116-72-1

S-Methyl (11β,16β,17α)-9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate

Description:

S-Methyl (11β,16β,17α)-9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate, with CAS number 87116-72-1, is a synthetic steroid compound that exhibits characteristics typical of glucocorticoids and anabolic steroids. This compound features a fluorine atom, hydroxyl groups, and a carbothioate moiety, which contribute to its biological activity and potential therapeutic applications. The presence of the 9-fluoro group enhances its potency and metabolic stability, while the hydroxyl groups may influence its interaction with steroid receptors. The structural modifications, including the methyl and keto groups, are significant for its pharmacological profile, potentially affecting its anti-inflammatory and anabolic properties. As a steroid derivative, it may also exhibit side effects commonly associated with steroid use, such as hormonal imbalances. Its specific applications and efficacy would depend on ongoing research and clinical studies, focusing on its role in treating conditions that require glucocorticoid or anabolic steroid intervention.

Formula: C₂₂H₂₉FO₄S

InChI: InChI=1S/C22H29FO4S/c1-12-9-16-15-6-5-13-10-14(24)7-8-19(13,2)21(15,23)17(25)11-20(16,3)22(12,27)18(26)28-4/h7-8,10,12,15-17,25,27H,5-6,9,11H2,1-4H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key: InChIKey=LNGNTCFORRWFSF-DVTGEIKXSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(SC)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• Androsta-1,4-diene-17-carbothioic acid, 9-fluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-methyl ester, (11β,16β,17α)-
• S-Methyl (11β,16β,17α)-9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate
• Timobesone [INN]
• Unii-97Tvb2O56G
• Timobesone

Timobesone

CAS: 87116-72-1

Timobesone is a topical corticosteroid.

Formula: C₂₂H₂₉FO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 408.53

Ref: TM-T13927

Timobesone

CAS: 87116-72-1

Timobesone is a peptide that can be used as a research tool in the study of ion channels and ligands. It interacts with the beta-2 adrenergic receptor and is an activator of this receptor. Timobesone has also been shown to activate other G protein-coupled receptors, such as the angiotensin II type 1 receptor, and to inhibit the activity of phosphodiesterase 4 (PDE4). This drug has been shown to bind to antibodies with high affinity and specificity.

Formula: C₂₂H₂₉FO₄S

Purity: Min. 95%

Molecular weight: 408.5 g/mol

Ref: 3D-MDA11672