CAS 87190-79-2

3'-azido-2',3'-dideoxy-5-methylcytidine

Description:

3'-Azido-2',3'-dideoxy-5-methylcytidine, commonly referred to as AZT or a derivative of cytidine, is a nucleoside analog with significant implications in antiviral therapy, particularly for HIV treatment. This compound features an azido group at the 3' position and lacks the hydroxyl group at the 2' and 3' positions, which is characteristic of dideoxynucleosides. The presence of a methyl group at the 5' position enhances its stability and bioactivity. As a nucleoside analog, it interferes with viral replication by incorporating into viral DNA, leading to chain termination during reverse transcription. Its mechanism of action is primarily due to its structural similarity to natural nucleosides, allowing it to be recognized by viral enzymes. The compound is typically administered in a phosphorylated form, which is essential for its antiviral activity. While it has shown efficacy in reducing viral load, potential side effects and resistance development are important considerations in its clinical use. Overall, 3'-azido-2',3'-dideoxy-5-methylcytidine represents a crucial advancement in the field of antiviral pharmacology.

Formula: C₁₀H₁₄N₆O₃

InChI: InChI=1/C10H14N6O3/c1-5-3-16(10(18)13-9(5)11)8-2-6(14-15-12)7(4-17)19-8/h3,6-8,17H,2,4H2,1H3,(H2,11,13,18)/t6-,7+,8+/m0/s1

Synonyms:

• 87190-79-2
• AzddMeC
• 3'-Azido-2',3'-dideoxy-4-deoxo-4-imino-5-methyluridine
• CS-92
• 3'-azido-2',3'-dideoxy-5-methylcytidine

AzddMeC

CAS: 87190-79-2

AzddMeC

Purity: ≥95%

Molecular weight: 266.26g/mol

Ref: 54-BUP07811

Azddmec

CAS: 87190-79-2

Please enquire for more information about Azddmec including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₀H₁₄N₆O₃

Purity: Min. 95%

Molecular weight: 266.26 g/mol

Ref: 3D-MDA19079

AzddMeC

CAS: 87190-79-2

AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection

Formula: C₁₀H₁₄N₆O₃

Purity: 97.14% - 99.62%

Color and Shape: Solid

Molecular weight: 266.26

Ref: TM-T26726