CAS 872-50-4

N-Methyl-2-pyrrolidone

Description:

N-Methyl-2-pyrrolidone (NMP) is a colorless to pale yellow liquid with a characteristic amine-like odor. It is a polar aprotic solvent, known for its ability to dissolve a wide range of organic and inorganic compounds, making it valuable in various industrial applications, including pharmaceuticals, coatings, and electronics. NMP has a high boiling point and low volatility, which contributes to its effectiveness as a solvent in high-temperature processes. Its chemical structure features a five-membered lactam ring, which contributes to its solvent properties and reactivity. NMP is miscible with water and many organic solvents, enhancing its versatility. However, it is important to note that NMP has raised health and environmental concerns due to its potential reproductive toxicity and skin irritation. As a result, its use is regulated in certain applications, and safety precautions are recommended when handling this substance. Overall, N-Methyl-2-pyrrolidone is a significant solvent in various fields, but its safety profile necessitates careful management.

Formula: C₅H₉NO

InChI: InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key: InChIKey=SECXISVLQFMRJM-UHFFFAOYSA-N

SMILES: O=C1N(C)CCC1

Synonyms:

• 1-Methyl-2-pyrrolidinone, anhydrous
• 1-Methyl-2-pyrrolidon
• 1-Methyl-2-pyrrolidone
• 1-Methyl-5-pyrrolidinone
• 1-Methylazacyclopentan-2-one
• 1-Methylpyrrolidone
• 1-Metil-2-Pirrolidona
• 2-Pyrolidinone, 1-methyl-
• 2-Pyrrolidinone, 1-methyl-
• 2-Pyrrolidone, 1-methyl-
• AgsolEx 1
• Ekos 1
• M 0418
• M-Pyrol
• M-Pyrol(R)
• M-pyrrole
• M-ピロール
• Methyl Pyrrolidon, N-
• Methylpyrrolidon, N-
• Metil-2-pirrolidona, N-
• Méthyle pyrrolidone, N-
• Microposit 2001
• N 0131
• N-Methyl pyrrolidone
• N-Methyl-2-Pyrrolidon
• N-Methyl-2-ketopyrrolidine
• N-Methyl-2-pyrrolidinone
• N-Methyl-2-pyrrolidone
• N-Methyl-α-pyrrolidinone
• N-Methyl-α-pyrrolidone
• N-Methyl-γ-butyrolactam
• N-Methylbutyrolactam
• N-Methylpyrolidone
• N-Methylpyrrolid-2-One
• N-Methylpyrrolidine-2-one
• N-Methylpyrrolidinone
• N-Methylpyrrolidnone
• N-Methylpyrrolidone
• N-Metil-2-Pirrolidone
• N-Metil-2-Pirrolidone (NMP)
• N-Metil-2-pirrolidona
• N-Metilpirrolidone
• N-メチル-2-ピロリドン
• N-メチルピロリドン
• NMP
• Nmp 1165
• Nmp-El
• Nmp-T
• Nsc 4594
• Pharmasolve
• Pyrol M
• Pyrrolidin-2-One, 1-Methyl-
• Sl 1332

1-Methyl-2-pyrrolidon

Controlled Product

CAS: 872-50-4

Formula: C₅H₉NO

Color and Shape: Neat

Molecular weight: 99.13

Ref: 04-C15143000

N-Methylpyrrolidone

Controlled Product

CAS: 872-50-4

Formula: C₅H₉NO

Color and Shape: Neat

Molecular weight: 99.13

Ref: 86-MM3004.00

N-Methylpyrrolidone

CAS: 872-50-4

N-Methylpyrrolidone, a cyclic amide, is a polar solvent for adhesives, paints, fuels, and drugs.

Formula: C₅H₉NO

Purity: 98.28%

Color and Shape: Clear Colorless Liquid

Molecular weight: 99.13

Ref: TM-T5851

N-Methyl-2-pyrrolidone, GlenPure™, analytical grade

CAS: 872-50-4

Formula: C₅H₉NO

Purity: ≥ 99.5%

Color and Shape: Clear, colourless liquid

Molecular weight: 99.13

Ref: 7W-GS3413

N-Methyl-2-pyrrolidone, GlenBiol™, suitable for molecular biology

CAS: 872-50-4

Formula: C₅H₉NO

Purity: ≥ 99.5%

Color and Shape: Clear, colourless liquid

Molecular weight: 99.13

Ref: 7W-GS5724

N-Methyl-2-pyrrolidone, GlenDry™, anhydrous over molecular sieve

CAS: 872-50-4

Formula: C₅H₉NO

Purity: ≥ 99.5%

Color and Shape: Clear, colourless to light-yellow liquid

Molecular weight: 99.13

Ref: 7W-GS4330

1-Methyl-2-pyrrolidinone

Controlled Product

CAS: 872-50-4

Applications It is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.
References Southwell, D., et al.: J. Pharm. Pharmacol., 33, 3 (1981), Barry, W., et al.: J. Invest. Dermatol., 82, 49 (1984),

Formula: C₅H₉NO

Color and Shape: Colourless

Molecular weight: 99.13

Ref: TR-M326120

N-Methyl-2-pyrrolidone

CAS: 872-50-4

N-Methyl-2-pyrrolidone is a solvent that is used in the production of polymers, paints, and other products. It has been shown to be a potent inducer of cardiac arrhythmias in rats. N-Methyl-2-pyrrolidone also has been shown to have a linear calibration curve for electrochemical impedance spectroscopy (EIS) data from 0.1 M to 5 M. This property makes it useful for determining reaction mechanisms and surface methodology. NMP has been shown to have constant pressure experimental solubility data, which can be used for thermodynamic data and high resistance values. NMP is not toxic to humans or animals at concentrations up to 2000 mg/kg body weight, but it does cause congestive heart failure in rats at doses of 500 mg/kg body weight or higher.

Formula: C₅H₉NO

Purity: Min. 98 Area-%

Color and Shape: Colorless Clear Liquid

Molecular weight: 99.13 g/mol

Ref: 3D-FM09696

N-Methyl-2-Pyrrolidone (NMP) Dried, 99%, water 0.005%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99%

Color and Shape: Clear, Colourless, Liquid (May darken on storage)

Molecular weight: 99.13

Ref: SR-96644

N-Methyl-2-Pyrrolidone (NMP) ACS, 99%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99%

Color and Shape: Clear, Colourless, Liquid, max. 50

Molecular weight: 99.13

Ref: SR-86263

N-Methyl-2-Pyrrolidone (NMP) for HPLC, 99.5%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.5%

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 99.13

Ref: SR-10331

N-Methyl-2-Pyrrolidone (NMP) GC-HS, 99.9%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.9 %

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 99.13

Ref: SR-25903

N-Methyl-2-Pyrrolidone (NMP) ExiPlus, Multi-Compendial, 99.5%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.5%

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 99.13

Ref: SR-11118

N-Methyl-2-Pyrrolidone (NMP) VLSI Semiconductor Grade, 99.5%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.5%

Color and Shape: Clear, Colourless, Liquid, max. 50

Molecular weight: 99.13

Ref: SR-90214

N-Methyl-2-Pyrrolidone (NMP) for molecular biology, 99.5%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.5%

Color and Shape: Clear, Colourless, Liquid, max. 20

Molecular weight: 99.13

Ref: SR-89975

N-Methyl-2-Pyrrolidone (NMP) extrapure, 99%

CAS: 872-50-4

Formula: C₅H₉NO

Purity: min. 99.5%

Color and Shape: Clear, Colourless, Liquid

Molecular weight: 99.13

Ref: SR-51369

1-Methyl-2-pyrrolidone-d6

Controlled Product

CAS: 872-50-4

Applications 1-Methyl-2-pyrrolidone-d6 is labeled 1-Methyl-2-pyrrolidone (M326120), which is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.
References Southwell, D., et al.: J. Pharm. Pharmacol., 33, 3 (1981); Barry, W., et al.: J. Invest. Dermatol., 82, 49 (1984),

Formula: C₅D₆H₃NO

Color and Shape: Neat

Molecular weight: 105.168

Ref: TR-M326124