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CAS 87226-41-3

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(-)-Etodolac

Description:
(-)-Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is classified as a chiral compound, with the (-) enantiomer being the active form that exhibits therapeutic effects. The substance functions by inhibiting cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. (-)-Etodolac is typically administered orally and is known for its relatively favorable gastrointestinal safety profile compared to other NSAIDs. Its chemical structure includes a carboxylic acid group, which contributes to its acidity and solubility characteristics. The drug is often prescribed for conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. Additionally, (-)-Etodolac has been studied for its potential effects on various inflammatory conditions beyond pain relief. As with all medications, it is essential to consider potential side effects and contraindications, and it should be used under the guidance of a healthcare professional.
Formula:C17H21NO3
InChI:InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)/t17-/m1/s1
InChI key:InChIKey=NNYBQONXHNTVIJ-QGZVFWFLSA-N
SMILES:C(C(O)=O)[C@]1(CC)C2=C(C=3C(N2)=C(CC)C=CC3)CCO1
Synonyms:
  • (1R)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
  • (-)-Etodolic acid
  • R-Etodolac
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1R)-
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (R)-
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Found 3 products.
  • (R)-Etodolac
    TLC
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    (R)-Etodolac

    CAS:
    Formula:C17H21NO3
    Molecular weight:287.36

    Ref: 4Z-E-056

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  • R(-) Etodolac
    Standalix
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    R(-) Etodolac

    CAS:
    Formula:C17H21NO3
    Molecular weight:287.35

    Ref: ST-EA-CP-E15013

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  • (R)-(-)-Etodolac
    TRC
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    (R)-(-)-Etodolac

    Controlled Product
    CAS:
    <p>Applications The R-enantiomer of Etodolac (E933090). Anti-inflammatory; analgesic.<br>References Boxenbaum, H., et al.: J. Pharmacokin. Biopharm., 10, 201 (1982), Iwatsubo, T., et al.: Biopharm. Drug Dispos., 17, 273 (1996), Obach, R., et al.: J. Pharmacol. Exp. Ther., 283, 46 (1997),<br></p>
    Formula:C17H21NO3
    Color and Shape:Neat
    Molecular weight:287.354

    Ref: TR-E933090

    5mg
    273.00€
    50mg
    1,875.00€