CAS 87233-61-2

Emedastine

Description:

Emedastine is an antihistamine compound primarily used in ophthalmic formulations for the treatment of allergic conjunctivitis. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, which is responsible for allergy symptoms. Emedastine is characterized by its ability to alleviate itching, redness, and swelling in the eyes caused by allergens. The substance is typically administered as eye drops, allowing for localized action with minimal systemic absorption. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. Emedastine is generally well-tolerated, with a low incidence of side effects, although some patients may experience mild ocular irritation. The compound is soluble in water, which facilitates its formulation in aqueous solutions for ophthalmic use. Overall, Emedastine represents a targeted approach to managing allergic reactions in the eyes, providing relief for individuals suffering from seasonal or perennial allergic conjunctivitis.

Formula: C₁₇H₂₆N₄O

InChI: InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3

InChI key: InChIKey=KBUZBQVCBVDWKX-UHFFFAOYSA-N

SMILES: C(COCC)N1C(=NC=2C1=CC=CC2)N3CCCN(C)CC3

Synonyms:

• 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
• 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-1H-benzimidazole
• 1-Methyl-4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepane
• 1-[2-(Ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole
• 1H-1,4-Diazepine, 1H-benzimidazole deriv.
• 1H-benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-
• 87233-61-2
• Rapimine
• Emedastine

1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole

CAS: 87233-61-2

Formula: C₁₇H₂₆N₄O

Purity: 97%

Molecular weight: 302.4145

Ref: IN-DA00GRJ2

Emedastine

CAS: 87233-61-2

Emedastine

Purity: ≥95%

Molecular weight: 302.41g/mol

Ref: 54-BUP12870

Emedastine

CAS: 87233-61-2

Formula: C₁₇H₂₆N₄O

Color and Shape: Pale Yellow Oil

Molecular weight: 302.42

Ref: 4Z-E-3414

Emedastine-13C-d3 Fumarate

CAS: 87233-61-2

Formula: C₁₆₁₃CH₂₃D₃N₄O·C₄H₄O₄

Color and Shape: Pale Yellow Solid

Molecular weight: 306.43 116.07

Ref: 4Z-E-343

Emedastine

CAS: 87233-61-2

Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.

Formula: C₁₇H₂₆N₄O

Purity: 97.1% - 97.76%

Color and Shape: Oil

Molecular weight: 302.41

Ref: TM-T3979