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CAS 87234-24-0

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Cinnoxicam

Description:
Cinnoxicam is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It belongs to the oxicam class of NSAIDs and is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins involved in inflammation and pain. Cinnoxicam is typically administered orally and is known for its relatively long half-life, allowing for less frequent dosing compared to some other NSAIDs. The compound exhibits good solubility in organic solvents, which can influence its formulation in pharmaceutical preparations. Its chemical structure includes a 2-oxazolidinone ring, contributing to its pharmacological activity. Cinnoxicam is often used in the treatment of conditions such as osteoarthritis and rheumatoid arthritis, providing relief from pain and inflammation. As with other NSAIDs, potential side effects may include gastrointestinal issues, cardiovascular risks, and renal impairment, necessitating careful consideration of patient history and concurrent medications.
Formula:C24H19N3O5S
InChI:InChI=1S/C24H19N3O5S/c1-27-22(24(29)26-20-13-7-8-16-25-20)23(18-11-5-6-12-19(18)33(27,30)31)32-21(28)15-14-17-9-3-2-4-10-17/h2-16H,1H3,(H,25,26,29)
InChI key:InChIKey=GPUVGQIASQNZET-UHFFFAOYSA-N
SMILES:O(C(C=CC1=CC=CC=C1)=O)C=2C=3C(S(=O)(=O)N(C)C2C(NC4=CC=CC=N4)=O)=CC=CC3
Synonyms:
  • 2H-1,2-Benzothiazine, 2-propenoic acid deriv.
  • SPA-S 510
  • 2-Propenoic acid, 3-phenyl-, 2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl ester, S,S-dioxide
  • 2-Propenoic acid, 3-phenyl-, 2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl ester
  • Piroxicam cinnamate (ester)
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