CAS 872363-17-2

Dipraglurant

Description:

Dipraglurant is a chemical compound that functions primarily as a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is characterized by its potential therapeutic applications, particularly in the treatment of neurological and psychiatric disorders, including Parkinson's disease and anxiety-related conditions. The compound is known for its ability to modulate glutamatergic signaling, which plays a crucial role in various brain functions. Dipraglurant exhibits a favorable pharmacokinetic profile, allowing for effective oral administration. Its chemical structure includes specific functional groups that contribute to its receptor-binding affinity and selectivity. Research has indicated that Dipraglurant may help alleviate certain symptoms associated with its target conditions, making it a subject of interest in clinical studies. However, as with any pharmacological agent, understanding its safety profile, potential side effects, and interactions with other medications is essential for its therapeutic use. Overall, Dipraglurant represents a promising avenue in the development of treatments for disorders linked to glutamate dysregulation.

Formula: C₁₆H₁₂FN₃

InChI: InChI=1S/C16H12FN3/c17-13-8-9-16-19-15(12-20(16)11-13)7-2-1-5-14-6-3-4-10-18-14/h3-4,6,8-12H,2,7H2

InChI key: InChIKey=LZXMUJCJAWVHPZ-UHFFFAOYSA-N

SMILES: C(CC#CC1=CC=CC=N1)C2=CN3C(=N2)C=CC(F)=C3

Synonyms:

• Dipraglurant
• 6-Fluoro-2-[4-(pyridin-2-yl)-3-butynyl]imidazo[1,2-a]pyridine
• 6-Fluoro-2-[4-(2-pyridinyl)-3-butyn-1-yl]imidazo[1,2-a]pyridine
• Imidazo[1,2-a]pyridine, 6-fluoro-2-[4-(2-pyridinyl)-3-butynyl]-
• Imidazo[1,2-a]pyridine, 6-fluoro-2-[4-(2-pyridinyl)-3-butyn-1-yl]-
• Icosabutate
• ADX48621
• ADX 48621

6-Fluoro-2-[4-(2-pyridinyl)-3-butyn-1-yl]imidazo[1,2-a]pyridine

CAS: 872363-17-2

Formula: C₁₆H₁₂FN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 265.2850

Ref: IN-DA00GU31

Dipraglurant

CAS: 872363-17-2

Dipraglurant

Purity: ≥98%

Molecular weight: 265.29g/mol

Ref: 54-BUP04065

Dipraglurant

CAS: 872363-17-2

Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.

Formula: C₁₆H₁₂FN₃

Purity: 98.7%

Color and Shape: Solid

Molecular weight: 265.29

Ref: TM-T15134