CAS 87249-11-4
:(+)-Etodolac
Description:
(+)-Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes (COX-1 and COX-2), which play a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. The substance is typically presented as a white to off-white crystalline powder and is soluble in organic solvents like ethanol and methanol, but has limited solubility in water. Its chemical structure features a chiral center, which contributes to its specific pharmacological activity. (+)-Etodolac is often prescribed for the management of conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. As with other NSAIDs, it may have side effects, including gastrointestinal discomfort and potential cardiovascular risks, necessitating careful consideration of its use in patients with certain health conditions. Overall, (+)-Etodolac is valued for its effectiveness in pain relief and inflammation reduction while requiring monitoring for adverse effects.
Formula:C17H21NO3
InChI:InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)/t17-/m0/s1
InChI key:InChIKey=NNYBQONXHNTVIJ-KRWDZBQOSA-N
SMILES:C(C(O)=O)[C@@]1(CC)C2=C(C=3C(N2)=C(CC)C=CC3)CCO1
Synonyms:- (+)-Etodolic acid
- Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (S)-
- S-Etodolac
- (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
- Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1S)-
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Found 2 products.
(S)-(+)-Etodolac
CAS:Controlled Product<p>Applications The S-enantiomer of Etodolac (E933090). Anti-inflammatory; analgesic.<br>References Boxenbaum, H., et al.: J. Pharmacokin. Biopharm., 10, 201 (1982), Iwatsubo, T., et al.: Biopharm. Drug Dispos., 17, 273 (1996), Obach, R., et al.: J. Pharmacol. Exp. Ther., 283, 46 (1997),<br></p>Formula:C17H21NO3Color and Shape:NeatMolecular weight:287.354
