CAS: 873054-44-5 - N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

Formula: C₂₄H₂₈N₂O₃

InChI: InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)

InChI key: InChIKey=PURKAOJPTOLRMP-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(O)=C(C=C1C(C)(C)C)C(C)(C)C)C2=CNC=3C=CC=CC3C2=O

Synonyms:

• 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-
• Ivacaftor
• Kalydeco
• N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide
• N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
• N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide
• N-[2,4-Di(tert-butyl)-5-hydroxyphenyl]-4-oxo-1H,4H-quinoline-3-carboxamide
• Vx-770

N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide

CAS: 873054-44-5

• Formula: C₂₄H₂₈N₂O₃
• Color and Shape: Solid
• Molecular weight: 392.4907

Ivacaftor

CAS: 873054-44-5

• Formula: C₂₄H₂₈N₂O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 392.50

Ivacaftor-d19

CAS: 1413431-22-7 873054-44-5

• Formula: C₂₄H₉D₁₉N₂O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 411.61

Ivacaftor

CAS: 873054-44-5

• Formula: C₂₄H₂₈N₂O₃
• Color and Shape: Neat
• Molecular weight: 392.49

Ivacaftor

CAS: 873054-44-5

Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR …

• Formula: C₂₄H₂₈N₂O₃
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 392.49

Ivacaftor

CAS: 873054-44-5

• Formula: C₂₄H₂₈N₂O₃
• Purity: ≤ 0.5%
• Color and Shape: White to off-white powder
• Molecular weight: 392.49

IVACAFTOR

CAS: 873054-44-5

• Purity: 95.0%
• Color and Shape: Liquid
• Molecular weight: 392.4989929199219

Ivacaftor

CAS: 873054-44-5

Applications Ivacaftor is used in the treatment of cystic fibrosis. References Clancy, J. et al.: …

• Formula: C₂₄H₂₈N₂O₃
• Color and Shape: Off-White
• Molecular weight: 392.49

Ivacaftor

CAS: 873054-44-5

Activates CFTR channels

• Formula: C₂₄H₂₈N₂O₃
• Purity: Min. 95%
• Color and Shape: White To Off-White Solid
• Molecular weight: 392.20999