CAS 87344-06-7
:Amtolmetin guacil
Description:
Amtolmetin guacil is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic and anti-inflammatory properties. It is characterized by its dual mechanism of action, which involves both the inhibition of cyclooxygenase enzymes (COX-1 and COX-2) and the modulation of the endocannabinoid system, contributing to its pain-relieving effects. The substance is often utilized in the treatment of conditions such as osteoarthritis and other musculoskeletal disorders. Amtolmetin guacil is known for its favorable gastrointestinal safety profile compared to traditional NSAIDs, making it a preferred choice for long-term management of pain. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The compound's chemical structure includes a guanidine moiety, which is integral to its pharmacological activity. As with any medication, potential side effects may include gastrointestinal discomfort, allergic reactions, or cardiovascular risks, necessitating careful consideration in patients with pre-existing conditions. Overall, Amtolmetin guacil represents a significant advancement in the field of pain management.
Formula:C24H24N2O5
InChI:InChI=1S/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
InChI key:InChIKey=CWJNMKKMGIAGDK-UHFFFAOYSA-N
SMILES:C(=O)(C=1N(C)C(CC(NCC(OC2=C(OC)C=CC=C2)=O)=O)=CC1)C3=CC=C(C)C=C3
Synonyms:- (2-Methoxyphenyl)2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate
- 2-Methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetamido)acetate
- 2-Methoxyphenyl N-{[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl}glycinate
- 87344-06-7
- Amtolmethin guacil
- Amtolmetin guacyl
- Finrid TM
- Glycine, N-[2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester
- Glycine, N-[[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester
- Med 15
- St 679
- See more synonyms
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Found 7 products.
2-Methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetamido)acetate
CAS:Formula:C24H24N2O5Purity:98%Color and Shape:SolidMolecular weight:420.4578Amtolmetin Guacil
CAS:Controlled Product<p>Applications Analgesic; anti-inflammatory used in the treatment of rheumatoid arthritis,<br>References Montrone, F., et al.: J. Int. Med. Res., 28, 91 (2000), Tubaro, E., et al.: Eur. J. Pharmacol., 467, 173 (2003), Cherkasov, A., et al.: Int. J. Mol. Sci., 6, 63 (2005),<br></p>Formula:C24H24N2O5Color and Shape:NeatMolecular weight:420.46Amtolmetin Guacil-d3
CAS:Controlled ProductFormula:C24D3H21N2O5Color and Shape:NeatMolecular weight:423.476Amtolmetin guacil
CAS:<p>Amtolmetin guacil is a nonsteroidal anti-inflammatory drug that belongs to the group of gsh-px activities. It is used to treat pain and inflammation in patients with inflammatory diseases. Amtolmetin guacil has shown efficacy in treatment trials for rheumatoid arthritis, osteoarthritis, and other inflammatory diseases. Amtolmetin guacil inhibits the activity of P-glycoprotein (Pgp), which is an important protein that transports drugs out of cells, thus increasing its bioavailability. Amtolmetin guacil also has low bioavailability due to its fast metabolism by liver enzymes and rapid excretion by the kidney. This drug can be administered as a nanoparticulate composition to increase its absorption into cells.</p>Formula:C24H24N2O5Purity:Min. 95%Molecular weight:420.46 g/molAmtolmetin guacil
CAS:<p>Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。</p>Formula:C24H24N2O5Purity:99.85%Color and Shape:White Needle-Shaped CrystalMolecular weight:420.46
