CAS 87475-54-5

5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester

Description:

5-[Bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester, with the CAS number 87475-54-5, is a synthetic organic compound characterized by its complex structure, which includes a benzimidazole core. This compound features a bis(2-chloroethyl)amino group, which is known for its reactivity and potential use in medicinal chemistry, particularly in the development of anticancer agents. The presence of the butanoic acid ethyl ester moiety suggests that it may exhibit lipophilic properties, enhancing its bioavailability. The compound's molecular structure indicates potential interactions with biological targets, making it of interest in pharmacological studies. Its chlorinated groups may also contribute to its biological activity, possibly influencing mechanisms such as DNA alkylation. As with many synthetic compounds, safety and handling precautions are essential due to potential toxicity associated with the chlorinated components. Overall, this compound represents a class of molecules that may have significant implications in therapeutic applications, particularly in oncology.

Formula: C₁₈H₂₅Cl₂N₃O₂

Synonyms:

• Bendamustine Impurity 11
• 5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
• Bendamustine impurity 7/Bendamustine Ethyl Ester/Bendamustine USP Related Compound I/Ethyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
• Bendamustine Ethyl Ester Q: What are the applications of
• Bendamustine USP RC I
• Bendamustine Related Impurity 11
• Bendamustine USP RC I (base))
• Bendamustin Impurity-I
• Bendamustine USP Related Compound I
• Bendamustine Ethyl Ester Q: What is the CAS Number of
• Bendamustine Ethyl EsterQ: What is
• Bendamustine Impurity 41
• Ethyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoate
• Bendamustine Ethyl Ester
• Bendamustine related impurities 11
• Bendamustine Ethyl Ester Q: What is the storage condition of

Bendamustine Related Compound I (Ethyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoate)

CAS: 87475-54-5

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₁₈H₂₅Cl₂N₃O₂

Color and Shape: White Solid

Molecular weight: 385.13238

Ref: 45-1065312

Bendamustine USP Related Compound I

CAS: 87475-54-5

Formula: C₁₈H₂₅Cl₂N₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 386.32

Ref: 4Z-B-4327

Bendamustine Ethyl Ester

CAS: 87475-54-5

Color and Shape: Neat

Ref: 86-MM0154.05

Bendamustine Ethyl Ester

Controlled Product

CAS: 87475-54-5

Impurity Bendamustine USP Related Compound I
Stability Moisture sensitive
Applications Bendamustine Ethyl Ester is an impurity of Bendamustine (B132500), which is used as an anticancer drug.
References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)

Formula: C₁₈H₂₅Cl₂N₃O₂

Color and Shape: Light Yellow To Beige

Molecular weight: 386.32

Ref: TR-B132495

Bendamustine USP Related Compound I

CAS: 87475-54-5

Formula: C₁₈H₂₅Cl₂N₃O₂

Molecular weight: 386.32

Ref: ST-EA-CP-B7009

Bendamustine ethyl ester

CAS: 87475-54-5

Bendamustine ethyl ester is a potent inhibitor of kinases in human urine. It is used in the treatment of cancer and tumors, as it has been shown to induce apoptosis in cancer cells. This drug is an analog of donepezil and has been found to inhibit several kinases, including protein kinase C and mitogen-activated protein kinase. Bendamustine ethyl ester has demonstrated anticancer activity against Chinese hamster ovary (CHO) cells and other cancer cell lines. It works by inhibiting DNA synthesis and inducing DNA damage, leading to cell cycle arrest and apoptosis. Bendamustine ethyl ester may be used in combination with other inhibitors for enhanced efficacy against cancer cells.

Formula: C₁₈H₂₅Cl₂N₃O₂

Purity: Min. 95%

Molecular weight: 386.3 g/mol

Ref: 3D-MDA47554