CAS 874880-25-8

6-(Trifluoromethoxy)-4-quinolinamine

Description:

6-(Trifluoromethoxy)-4-quinolinamine is a chemical compound characterized by its quinoline structure, which consists of a bicyclic aromatic system. The presence of the trifluoromethoxy group (-OCF3) at the 6-position of the quinoline ring significantly influences its chemical properties, including its reactivity and solubility. This compound typically exhibits a range of biological activities, making it of interest in medicinal chemistry and drug development. The trifluoromethoxy group can enhance lipophilicity and metabolic stability, potentially improving the pharmacokinetic profile of derivatives. Additionally, the amino group (-NH2) at the 4-position can participate in hydrogen bonding and further functionalization, allowing for the synthesis of various analogs. The compound's molecular structure contributes to its potential applications in pharmaceuticals, particularly in targeting specific biological pathways. As with many fluorinated compounds, it may also exhibit unique interactions with biological systems due to the electronegative fluorine atoms, which can affect binding affinity and selectivity.

Formula: C₁₀H₇F₃N₂O

InChI: InChI=1S/C10H7F3N2O/c11-10(12,13)16-6-1-2-9-7(5-6)8(14)3-4-15-9/h1-5H,(H2,14,15)

InChI key: InChIKey=KDFPUZKVCMQYIU-UHFFFAOYSA-N

SMILES: NC=1C2=C(C=CC(OC(F)(F)F)=C2)N=CC1

Synonyms:

• 4-Quinolinamine, 6-(Trifluoromethoxy)-
• 6-(Trifluoromethoxy)-4-quinolinamine

4-Amino-6-trifluoromethoxyquinoline

CAS: 874880-25-8

4-Amino-6-trifluoromethoxyquinoline

Purity: ≥95%

Molecular weight: 228.17g/mol

Ref: 54-PC404578

6-(Trifluoromethoxy)quinolin-4-amine

CAS: 874880-25-8

Purity: 95+%

Molecular weight: 228.173996

Ref: 10-F726188