CAS 875-74-1

(-)-Phenylglycine

Description:

(-)-Phenylglycine, with the CAS number 875-74-1, is an amino acid derivative characterized by its chiral nature, existing as a single enantiomer. It features a phenyl group attached to the alpha carbon of glycine, which contributes to its unique properties. This compound is typically a white crystalline solid and is soluble in water, reflecting its polar characteristics due to the amino and carboxylic acid functional groups. The presence of the phenyl group enhances its hydrophobic interactions, making it useful in various biochemical applications. (-)-Phenylglycine is often employed in the synthesis of pharmaceuticals and as a building block in peptide synthesis. Additionally, it can serve as a chiral auxiliary in asymmetric synthesis, aiding in the production of enantiomerically pure compounds. Its biological significance is also notable, as it can act as a neurotransmitter or modulator in certain pathways. Overall, (-)-Phenylglycine is a versatile compound with applications in both research and industry, particularly in the fields of organic chemistry and medicinal chemistry.

Formula: C₈H₉NO₂

InChI: InChI=1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m1/s1

InChI key: InChIKey=ZGUNAGUHMKGQNY-SSDOTTSWSA-N

SMILES: [C@@H](C(O)=O)(N)C1=CC=CC=C1

Synonyms:

• (-)-(R)-Phenylglycine
• (-)-Phenylglycine
• (2R)-2-Amino-2-phenylacetic acid
• (2R)-2-Azaniumyl-2-phenylacetate
• (2R)-Amino-2-phenylethanoic acid
• (2R)-amino(phenyl)ethanoic acid
• (R)-(-)-2-Phenylglycine
• (R)-(-)-alpha-Aminophenylacetic acid
• (R)-2-Amino-2-(phenyl)ethanoic acid
• (R)-2-Amino-2-phenylacetic acid
• (R)-2-Amino-2-phenylethanoic acid
• (R)-2-Phenyl-2-aminoethanoic acid
• (R)-α-Aminobenzeneacetic acid
• (R)-α-Phenylglycine
• (αR)-α-Aminobenzeneacetic acid
• <span class="text-smallcaps">D</span>-(-)-2-Phenylglycine
• <span class="text-smallcaps">D</span>-(-)-Aminophenylacetic acid
• <span class="text-smallcaps">D</span>-(-)-Phenylglycine
• <span class="text-smallcaps">D</span>-(-)-α-Aminophenylacetic acid
• <span class="text-smallcaps">D</span>-(-)-α-Phenylglycine
• <span class="text-smallcaps">D</span>-C-Phenylglycine
• Benzeneacetic acid, α-amino-, (R)-
• Benzeneacetic acid, α-amino-, (αR)-
• D-(-)-Alpha-Phenylglycin
• D-(-)-Aminobenzeneacetic Acid
• D-(-)-Aminophenylacetic acid
• D-(-)-Α-Phenylglycine
• D-(-)-α-Aminophenylacetic acid
• D-(-)-α-Phenylglycin
• D-(-)-α-fenilglicina
• D-2-phenylglycine
• D-C-Phenylglycine
• D-Phenyl Glycine
• D-Phenylglycine
• Glycine, 2-Phenyl-, (R)-(-)-
• Glycine, 2-phenyl-, <span class="text-smallcaps">D</span>-
• Glycine, 2-phenyl-, D-
• H-D-Phg-OH
• R-Aminobenzeneacetic Acid
• D-(-)-alpha-Phenylglycine

D-(-)-2-Phenylglycine, 99%

CAS: 875-74-1

D-(-)-2-Phenylglycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Used to prepare semisynthetic antibiotics amoxicillin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₈H₉NO₂

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 151.17

Ref: 02-A15669

H-D-Phg-OH

CAS: 875-74-1

Formula: C₈H₉NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 151.1626

Ref: IN-DA003C8R

(2R)-2-Amino-2-phenyl-acetic acid

CAS: 875-74-1

(2R)-2-Amino-2-phenyl-acetic acid

Purity: 98.5%

Molecular weight: 151.16g/mol

Ref: 54-OR480329

Cefalexin (Cephalexin) EP Impurity A (Ampicillin EP Impurity L)

CAS: 875-74-1

Formula: C₈H₉NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 151.17

Ref: 4Z-C-4715

D-(-)-α-Phenylglycine

CAS: 875-74-1

Formula: C₈H₉NO₂

Purity: (HPLC) ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 151.17

Ref: 7W-GM2165

(2R)-2-Amino-2-phenylacetic Acid (D-Phenylglycine)

Controlled Product

CAS: 875-74-1

Formula: C₈H₉NO₂

Color and Shape: White

Molecular weight: 151.16

Ref: 86-MM0253.12

D-(-)-2-Phenylglycine

Controlled Product

CAS: 875-74-1

Impurity Cefalexin EP Impurity A / Ampicillin EP Impurity L
Applications D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
References Wang, L., et al.: Enzyme. Microb. Technol., 51, 107 (2012); Koide, H., et al.: J. Antibotics., 65, 91 (2012); Adediran, S.A., et al.: Biochem., 50, 376 (2011);

Formula: C₈H₉NO₂

Color and Shape: White

Molecular weight: 151.16

Ref: TR-P327125

D(-)-a-Phenylglycine

CAS: 875-74-1

D-a-Phenylglycine is a D-amino acid that is synthesized by the enzyme phenylalanine ammonia lyase from the amino acid phenylalanine. It is an intermediate in the synthesis of dopamine and norepinephrine, which are neurotransmitters involved in regulating mood, behavior, and cognition. D-a-Phenylglycine has been shown to have structural activity against dopamine receptors and response elements. It also has a high binding affinity for human serum proteins and can be used in surface methodology as well as x-ray diffraction data. In addition, it has been shown to have strong inhibitory effects on microbial metabolism due to its structural similarity to sugar molecules.

Formula: C₈H₉NO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 151.16 g/mol

Ref: 3D-FP40302

H-D-Phg-OH

CAS: 875-74-1

M03223 - H-D-Phg-OH

Formula: C₈H₉NO₂

Purity: 97%

Color and Shape: White powder

Molecular weight: 151.165

Ref: 10-M03223

Cefalexin EP Impurity A

CAS: 875-74-1

Formula: C₈H₉NO₂

Molecular weight: 151.16

Ref: ST-EA-CP-C159001

Cefaclor EP Impurity A

CAS: 875-74-1

Formula: C₈H₉NO₂

Molecular weight: 151.16

Ref: ST-EA-CP-C60001

D-2-Phenylglycine

CAS: 875-74-1

Formula: C₈H₉NO₂

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 151.17

Ref: 3B-P0820