CAS 875467-41-7

Imidazo[1,2-a]quinazolin-2(1H)-one,6,7-dichloro-3,5-dihydro-1-hydroxy-

Description:

Imidazo[1,2-a]quinazolin-2(1H)-one, 6,7-dichloro-3,5-dihydro-1-hydroxy- is a heterocyclic compound characterized by its fused imidazole and quinazoline rings. This compound features dichloro substituents at the 6 and 7 positions, which can influence its biological activity and solubility. The presence of a hydroxy group at the 1-position contributes to its potential reactivity and interaction with biological targets. Typically, compounds of this class may exhibit various pharmacological properties, including antimicrobial, anti-inflammatory, or anticancer activities, making them of interest in medicinal chemistry. The molecular structure suggests that it may engage in hydrogen bonding due to the hydroxy group, which can enhance its interaction with biological macromolecules. Additionally, the dichloro groups may affect the electronic properties of the molecule, potentially influencing its binding affinity to specific receptors or enzymes. Overall, this compound represents a unique scaffold for further exploration in drug development and therapeutic applications.

Formula: C₁₀H₇Cl₂N₃O₂

6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-a]quinazolin-2(1H)-one (Anagrelide Impurity)

Controlled Product

CAS: 875467-41-7

Applications 1-Hydroxy Anagrelide, is an intermediate for the synthesis of 3-Hydroxy Anagrelide, a major metabolite of Anagrelide, an antithrombotic.
References Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979), Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al.: Drugs, 47, 809 (1994),

Formula: C₁₀H₇Cl₂N₃O₂

Color and Shape: Neat

Molecular weight: 272.09

Ref: TR-D434345