CAS 875468-81-8
:6-fluoro-2-(pyridin-2-yl)-1H-benzimidazole
Description:
6-Fluoro-2-(pyridin-2-yl)-1H-benzimidazole is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with a fluorine atom and a pyridine ring. The presence of the fluorine atom typically enhances the compound's lipophilicity and may influence its biological activity. The benzimidazole moiety is known for its role in various pharmacological applications, including as an anti-parasitic and anti-cancer agent. The pyridine ring contributes to the compound's aromaticity and can participate in hydrogen bonding, potentially affecting its solubility and reactivity. This compound may exhibit interesting properties such as fluorescence, making it useful in various applications, including medicinal chemistry and material science. Additionally, its specific interactions with biological targets can be explored for therapeutic purposes. Overall, 6-fluoro-2-(pyridin-2-yl)-1H-benzimidazole represents a versatile structure with potential implications in drug development and chemical research.
Formula:C12H8FN3
InChI:InChI=1/C12H8FN3/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,(H,15,16)
SMILES:c1ccnc(c1)c1nc2ccc(cc2[nH]1)F
Synonyms:- 1H-benzimidazole, 5-fluoro-2-(2-pyridinyl)-
- 1H-benzimidazole, 6-fluoro-2-(2-pyridinyl)-
- 5-fluoro-2-(pyridin-2-yl)-1H-benzimidazole
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Found 4 products.
5-Fluoro-2-(2-pyridyl)-1h-benzimidazole
CAS:Formula:C12H8FN3Purity:97%Color and Shape:SolidMolecular weight:213.21045-Fluoro-2-(2-pyridyl)-1H-benzimidazole
CAS:5-Fluoro-2-(2-pyridyl)-1H-benzimidazolePurity:97%Molecular weight:213.21g/mol5-Fluoro-2-(2-pyridyl)-1H-benzimidazole
CAS:5-Fluoro-2-(2-pyridyl)-1H-benzimidazole is a compound that has been used in the synthesis of metronidazole. It can be synthesized by reacting pyridine with lead molecules and equimolar amounts of carboxaldehyde and 2,5-difluorobenzene. The filtrate is then purified by recrystallization to yield 5-fluoro-2-(2-pyridyl)-1H-benzimidazole. This compound can also be obtained from the reaction of 1,4-dihydropyridine with hydrogen fluoride. 5FBA has been used in the synthesis of other drugs such as clozapine and fluoxetine.Formula:C12H8FN3Purity:Min. 95%Molecular weight:213.21 g/mol



