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CAS 87638-04-8

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Carumonam

Description:
Carumonam is a synthetic antibiotic belonging to the class of beta-lactam compounds, specifically a monobactam. It is primarily characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a range of Gram-negative bacteria. Carumonam exhibits stability against certain beta-lactamases, which are enzymes produced by bacteria that can inactivate many other antibiotics. This characteristic enhances its therapeutic potential, particularly in treating infections caused by resistant strains. The compound is typically administered via injection and has been studied for its pharmacokinetics, including absorption, distribution, metabolism, and excretion. Its safety profile and side effects are similar to those of other beta-lactams, though individual responses may vary. Carumonam's efficacy and safety in clinical settings have been the subject of research, particularly in the context of multidrug-resistant infections. Overall, its unique properties make it a valuable option in the antibiotic arsenal, especially for patients with limited treatment alternatives.
Formula:C12H14N6O10S2
InChI:InChI=1S/C12H14N6O10S2/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26)/b17-7-/t5-,8+/m1/s1
InChI key:InChIKey=UIMOJFJSJSIGLV-JNHMLNOCSA-N
SMILES:N(C(/C(=N\OCC(O)=O)/C=1N=C(N)SC1)=O)[C@H]2[C@@H](COC(N)=O)N(S(=O)(=O)O)C2=O
Synonyms:
  • ({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-({(3S)-2-[(carbamoyloxy)methyl]-4-oxo-1-sulfoazetidin-3-yl}amino)-2-oxoethylidene]amino}oxy)acetic acid
  • 2-[[(Z)-[2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
  • Acetic acid, 2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • Acetic acid, [[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, [2S-[2α,3α(Z)]]-
  • Ama 1080
  • Antibiotic Ro 17-2301
  • Ro 17-2301
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Found 2 products.
  • Carumonam
    Targetmol
    + Info

    Carumonam

    CAS:
    <p>Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.</p>
    Formula:C12H14N6O10S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:466.40

    Ref: TM-T20751

  • Carumonam
    Biosynth
    + Info

    Carumonam

    CAS:
    <p>Carumonam is a synthetic monobactam antibiotic, which is derived from chemically modifying aztreonam to enhance its antimicrobial properties. Its source is entirely synthetic, allowing for precise structural modifications to target specific bacterial pathogens. The mode of action involves the inhibition of bacterial cell wall synthesis. Carumonam binds to penicillin-binding proteins (PBPs) on the surface of bacterial cell walls, disrupting the peptidoglycan cross-linking process necessary for cell wall strength and integrity. This action results in bacterial cell lysis and death, making it effective against a range of Gram-negative bacteria.</p>
    Formula:C12H14N6O10S2
    Purity:Min. 95%
    Molecular weight:466.41 g/mol

    Ref: 3D-AC29443

    1g
    12,672.00€