CAS 87638-04-8: Carumonam

Description:Carumonam is a synthetic antibiotic belonging to the class of beta-lactam compounds, specifically a monobactam. It is primarily characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a range of Gram-negative bacteria. Carumonam exhibits stability against certain beta-lactamases, which are enzymes produced by bacteria that can inactivate many other antibiotics. This characteristic enhances its therapeutic potential, particularly in treating infections caused by resistant strains. The compound is typically administered via injection and has been studied for its pharmacokinetics, including absorption, distribution, metabolism, and excretion. Its safety profile and side effects are similar to those of other beta-lactams, though individual responses may vary. Carumonam's efficacy and safety in clinical settings have been the subject of research, particularly in the context of multidrug-resistant infections. Overall, its unique properties make it a valuable option in the antibiotic arsenal, especially for patients with limited treatment alternatives.

Formula:C₁₂H₁₄N₆O₁₀S₂

InChI:InChI=1S/C12H14N6O10S2/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26)/b17-7-/t5-,8+/m1/s1

InChI key:InChIKey=UIMOJFJSJSIGLV-JNHMLNOCSA-N

SMILES:O=C(OCC1N(C(=O)C1NC(=O)C(=NOCC(=O)O)C=2N=C(SC2)N)S(=O)(=O)O)N

Synonyms:
({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-({(3S)-2-[(carbamoyloxy)methyl]-4-oxo-1-sulfoazetidin-3-yl}amino)-2-oxoethylidene]amino}oxy)acetic acid
2-[[(Z)-[2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
Acetic acid, 2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
Acetic acid, [[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, [2S-[2α,3α(Z)]]-
Ama 1080
Antibiotic Ro 17-2301
Ro 17-2301