CAS 876685-78-8

Piperazine, 1-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-(2-pyridinyl)-

Description:

Piperazine, 1-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-(2-pyridinyl)-, identified by CAS number 876685-78-8, is a chemical compound that features a piperazine core substituted with a phenyl group and a pyridine moiety. This compound is characterized by its oxadiazole ring, which contributes to its potential biological activity and chemical stability. The presence of the oxadiazole group often enhances the compound's properties, such as solubility and reactivity, making it of interest in medicinal chemistry. Piperazine derivatives are known for their diverse pharmacological activities, including anti-anxiety, anti-depressant, and anti-microbial effects. The specific substitution patterns in this compound may influence its interaction with biological targets, potentially leading to unique therapeutic applications. Additionally, the compound's molecular structure suggests it may exhibit specific physical properties, such as melting point and solubility, which are important for its practical use in research and development. Overall, this compound represents a class of piperazine derivatives that could be explored for various applications in pharmaceuticals and biochemistry.

Formula: C₁₈H₁₉N₅O

Synonyms:

• Piperazine, 1-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-(2-pyridinyl)-

AChE-IN-63

CAS: 876685-78-8

AChE-IN-63 (Compound 5AD) serves as a selective inhibitor of hAChE, exhibiting an IC 50 value of 0.103 μM. Moreover, it inhibits hBChE and hBACE-1 with IC 50 values of 10 μM and 1.342 μM, respectively. AChE-IN-63 is effective in inhibiting Aβ aggregation and preventing the formation and deposition of Aβ1-42. It can effectively penetrate the blood-brain barrier and is orally bioavailable. This compound is primarily utilized in research related to Alzheimer's disease [1].

Formula: C₁₈H₁₉N₅O

Color and Shape: Solid

Molecular weight: 321.38

Ref: TM-T85555